Publications by authors named "Maher Khaldi"
Diverticulitis: A Review of Current and Emerging Practice-Changing Evidence.
Clin Colon Rectal Surg
November 2024
Article Synopsis
- Acute diverticulitis is a common colorectal emergency in the Western world, and its management has evolved significantly over time.
- Recent evidence emphasizes the importance of the microbiome and genetic factors in understanding the disease, while traditional antibiotic use for uncomplicated cases may no longer be necessary.
- There are shifts in the recommendations for follow-up procedures, like colonoscopy, which now only applies to specific patient groups, though there are still gaps in understanding certain forms of the disease.
Background And Objectives: EUS is a potential alternative for the drainage of abscesses. The aim of this study was to determine if EUS-guided pelvic abscess drainage is technically feasible, safe, and a valid option for abscess resolution.
Methods: We conducted a retrospective review from 2002 to 2020 at a single quaternary institution.
NK cells are innate immune cells that target infected and tumor cells. Mature NK (mNK) cells undergo functional maturation characterized by four distinct stages, during which they acquire their cytotoxic properties. mNK cells from non-obese diabetic (NOD) mice exhibit a defect in functional maturation and have impaired cytotoxic functions.
View Article and Find Full Text PDFIntroduction: Peritoneal mesothelioma (PM) is a rare malignancy originating from the peritoneal lining. Cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC) is the standard-of-care for patients with isolated PM. Due to a paucity of prospective data there are several different HIPEC protocols.
View Article and Find Full Text PDFCytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is a treatment option for peritoneal metastases (PM) but is associated with significant postoperative morbidity. The aim of this study was to determine the prognostic value of computed tomographic (CT)-measured sarcopenia on postoperative outcomes and survival in patients undergoing CRS-HIPEC for PM from various origins. A retrospective cohort study was conducted between 2012 and 2020.
View Article and Find Full Text PDFArticle Synopsis
- There is ongoing debate on the best methods to lower central venous pressure during liver surgery, which can help reduce blood loss and the need for blood transfusions.
- A study analyzed data from cancer patients undergoing hepatectomy between 2011 and 2017 to evaluate the impact of intraoperative hypovolemic phlebotomy (IOHP) on blood transfusion needs and surgical outcomes.
- Results showed that patients who received IOHP had a lower risk of needing transfusions on the day of surgery compared to those who did not (6.9% vs. 12.4%), although the overall incidence of severe postoperative complications was similar between the two groups.
Although postoperative abdominal drains are useful in therapeutic settings, their prophylactic role is debatable. We herein describe the case of a 30-year-old male who underwent bile duct resection with hepaticojejunostomy for cholangiocarcinoma. On postoperative day four, the patient developed biliary peritonitis.
View Article and Find Full Text PDFPurpose: To compare the rate of remission, rate of response, change in depressive symptoms, and adverse effects between repetitive transcranial magnetic stimulation (rTMS) and electroconvulsive therapy (ECT).
Materials And Methods: In this retrospective case-control study, 35 patients treated for depression with rTMS (left dorsolateral prefrontal cortex, 90% observed motor threshold, 10 Hz, 2000 pulses/session, 15 sessions) at Örebro University Hospital, Sweden (cases), were compared with a matched group of 35 patients treated for depression with ECT (controls). Data on controls were obtained from the Swedish National Quality Register for ECT (Q-ECT).
Introduction: A tailgut cyst, also called retrorectal cystic hamartoma, is a rare congenital lesion that forms most commonly in the retrorectal space. It is presumed to arise from remnants of early embryogenesis.
Presentation Of Case: The following report describes a unique case of a retrorectal cystic hamartoma in a 53 year-old French Canadian man with a history of low back pain.