Publications by authors named "Mahenintsoa Rakotondrazaka"

Article Synopsis
  • Taenia solium infections, including taeniosis and cysticercosis, are prevalent yet underdiagnosed in rural Madagascar, particularly around Ranomafana National Park, prompting a study to evaluate their prevalence and risk factors.
  • A cross-sectional survey conducted in June 2016 revealed that 10 out of 459 participants had Taenia spp. eggs in their stool, predominantly the Asian genotype of T. solium, while seroprevalence of cysticercosis showed 27.5% to 29.8% of participants had specific antibodies.
  • Key risk factors identified included open defecation, large household sizes, and age over 15 years, while females and reliance on river
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Objective: Taenia solium (Ts) cysticercosis is a neglected zoonotic disease particularly prevalent in Madagascar. Few data are available for children, current data mainly rely on antibody prevalence. We sought to determine the Ts-antigen seroprevalence-determining active cysticercosis-amongst school children from various cities in Madagascar (excluding the capital) and evaluated associated risk factors.

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This study aimed to evaluate 5 enzyme immunoassays for detecting human antibodies against Taenia solium in human serum and for the diagnosis of neurocysticercosis (NCC): DRG™, RIDASCREEN™, NOVATECH™, CYPRESS™, and IVD™. A collection of 114 reference serum samples were used. All sera were tested both by ELISA and by an immunoblot method (enzyme-linked immunoelectrotransfer blot [EITB]).

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Cysticercosis is a zoonotic disease due to Taenia solium, which involves porcines as intermediate host. It is endemic in Madagascar, however minimal data has been reported concerning porcine cysticercosis prevalence. Lack of ante-mortem diagnostic tools renders the evaluation of its prevalence difficult.

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