Hospital based prospective longitudinal clinical and immunologic study of 179 patients of primary anti-phospholipid syndrome.

Aim: To study the clinical and immunological features of primary antiphospholipid syndrome (APS), and to analyze the differences between primary APS and APS associated with autoimmune rheumatic disease (ARD/APS).

Methods: This prospective, longitudinal study, carried out from December 2004 to July 2011 included 179 patients with primary APS and 52 patients of ARD/APS diagnosed as per modified 2006 Sapporo's Criteria.

Results: Out of 179 patients of primary APS, 12 were male and 167 were female.