Publications by authors named "Mahendra Eko Saputra"
Article Synopsis
- The systematic review assesses the effectiveness of single provisional versus dual-systematic stenting for left main (LM) bifurcation disease despite recent advancements in the field.
- It analyzed data from 22 studies with a total of 10,776 participants and found no significant differences in all-cause mortality, cardiovascular mortality, and other major cardiovascular events between the two stenting strategies.
- The review highlights that while the outcomes are comparable, further research is needed to confirm the results of new stenting techniques, especially given the variability seen in cohort studies.
C-Reactive Protein (CRP)-albumin ratio (CAR) is a novel prognostic biomarker that is predicted to be a more reliable indicator than CRP or albumin alone. Therefore, this systematic review aimed to evaluate the role of CAR in predicting poor outcomes of heart failure (HF) patients. We conducted a literature search across ProQuest, PubMed, ScienceDirect, Web of Science, and Scopus.
View Article and Find Full Text PDFThe association between long-term systolic blood pressure variability (SBPV) and cardiovascular (CV) outcomes after being adjusted with mean blood pressure (BP) is questionable. This systematic review aims to evaluate the associations between mean BP adjusted long-term SBPV and CV outcomes. A systematic search was conducted on PubMed, Scopus, and Science Direct on January 4, 2023.
View Article and Find Full Text PDFArticle Synopsis
- Current research indicates that the gut microbiome (GM) plays a significant role in the development of atherosclerosis, particularly through the metabolite trimethylamine-N-oxide (TMAO), which enhances plaque formation and vascular dysfunction.
- TMAO promotes inflammation and oxidative stress in blood vessels, leading to increased vulnerability of atherosclerotic plaques.
- Potential treatments include using compounds like DMB, IMC, and FMC to reduce TMAO levels and combined strategies targeting TMAO production, aiming for novel prevention methods for cardiovascular disease.