The role of noncoding RNAs in metabolic reprogramming of cancer cells.

Metabolic reprogramming is a well-known feature of cancer that allows malignant cells to alter metabolic reactions and nutrient uptake, thereby promoting tumor growth and spread. It has been discovered that noncoding RNAs (ncRNAs), including microRNA (miRNA), long noncoding RNA (lncRNA), and circular RNA (circRNA), have a role in a variety of biological functions, control physiologic and developmental processes, and even influence disease. They have been recognized in numerous cancer types as tumor suppressors and oncogenic agents.

MNDL Sparsity Order Selection for Compressed Sensing with Application in ECG Compression.

One of the main challenges in sparse signal recovery in compressed sensing framework is determining the sparsity order. Most model order selection methods introduce a penalty term for the number of parameters, however do not consider the variance of the observation and measurement noise. Minimum Noiseless Description Length (MNDL), on the other hand, considers these factors and provides a more robust results in order selection.

Association of IFN-γ and P2X7 Receptor Gene Polymorphisms in Susceptibility to Tuberculosis Among Iranian Patients.

Interferon-gamma (IFN-γ) and P2X7 receptor are crucial for host defence against mycobacterial infections. Recent studies have indicated that IFN-γ, IFN-γ receptor 1 (IFN-γR1) andP2X7 gene polymorphisms are associated with susceptibility to pulmonary tuberculosis (TB). However, the relationship between IFN-γ and P2X7 polymorphism and TB susceptibility remains inconclusive in Iranian population.