Publications by authors named "Mahdi Khorasani"

Article Synopsis
  • The elderly population in Seoul increased from 1.4 million to 1.7 million between 2018 and 2023, and there is a notable rise in elderly taxi drivers, leading to more safety concerns due to increased fatal and severe injury crashes linked to them.
  • A study aimed to investigate the stability of factors affecting at-fault crash injury severity among elderly and non-elderly taxi drivers over time, utilizing data from 2017 to 2023 in Seoul.
  • Risk factors such as late-night driving, dry roads, traffic signal violations, and higher speed limits were identified as significantly increasing the likelihood of severe crashes, with the presence of elderly not-at-fault drivers greatly elevating crash severity when involved with
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Objectives: The aim of this study was to investigate the effects of nutritional saffron (Crocus sativus L.) stigma hydroalcoholic extract on blood pressure (BP) and histology of the aorta in normotensive and hypertensive rats.

Materials And Methods: Saffron (200 mg/kg/day) was given orally for 5 weeks to normotensive and hypertensive rats.

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Previous experimental studies have shown the protective effects of CBX on brain ischemic injures in global and in vitro models of ischemia. However, effects of CBX in temporary model of focal cerebral ischemia are not clear. Hence, the aim of this study was to investigate the effects of central microinjection of CBX on post-ischemic reperfusion injuries in a temporary model of focal cerebral ischemia.

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Carbenoxolone (CBX) has a neuroprotective effect in experimental models of brain ischemia and trauma. However, systemic effect of CBX on ischemic reperfusion injuries has not been investigated in a temporary model of focal cerebral ischemia. Male Wistar rats (n = 32) were divided into control and CBX-treated (100, 200, or 400 mg/kg, intraperitoneally) groups.

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The present research aimed at investigating the opioid-adenosine interaction on regional cerebral blood flow (rCBF). Therefore rCBF in the sensory cortex of morphine-naive and -dependent rats was measured using the laser-Doppler flowmetry technique. The results showed that adenosine (10(-5), 10(-4), 10(-3) M) significantly increased rCBF in morphine-dependent rats (MDR) (P < 0.

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