Numerical simulation and mathematical modeling of biomechanical stress distribution in poroelastic tumor tissue via magnetic field and bio-ferro-fluid.

Based on scientific evidence, it seems that bio-magnetic systems can change the process of cancer cell death by affecting the distribution of pressure and mechanical stress in the tumor tissue. Already most of the research has been done experimentally and few mathematical modeling and numerical simulations have been done to investigate the relationship between the magnetic parameters and the mechanical stress of the tumor tissue. This is despite the fact that in order to be able to make new equipment with the help of medical engineering methods, it is definitely necessary that the mathematics governing the problem and changes in the effective magnetic parameters (such as the shape of the magnetic source, magnetic flux density, magnetic source distance and ferro-fluid volume fraction) should be studied as much as possible.

Modeling the Endothelial Glycocalyx Layer in the Human Conventional Aqueous Outflow Pathway.

A layer of proteoglycans and glycoproteins known as glycocalyx covers the surface of the trabecular meshwork (TM), juxtacanalicular tissue (JCT), and Schlemm's canal (SC) inner wall of the conventional aqueous outflow pathway in the eye. This has been shown to play a role in the mechanotransduction of fluid shear stress and in the regulation of the outflow resistance. The outflow resistance in the conventional outflow pathway is the main determinant of the intraocular pressure (IOP) through an active, two-way, fluid-structure interaction coupling between the outflow tissues and aqueous humor.

A combination of experimental and finite element analyses of needle-tissue interaction to compute the stresses and deformations during injection at different angles.

One of the main clinical applications of the needles is its practical usage in the femoral vein catheterization. Annually more than two million peoples in the United States are exposed to femoral vein catheterization. How to use the input needles into the femoral vein has a key role in the sense of pain in post-injection and possible injuries, such as tissue damage and bleeding.