A novel formulation of Mtb72F DNA vaccine for immunization against tuberculosis.

Objectives: (), an intracellular pathogen, causes 1.5 million deaths globally. Bacilli Calmette-Guérin (BCG) is commonly administered to protect people against infection; however, there are some obstacles with this first-generation vaccine.

Construction of Mtb72F Plasmid as a DNA Vaccine Candidate for .

Background: With one-third of the world's population infected, tuberculosis (TB) is one of the most common infectious diseases and a major public health problem, especially in developing countries. The efficacy of the BCG vaccine for controlling the disease in adults is poor. The development of an effective TB vaccine is a global objective.

Study on imipenem resistance and prevalence of blaVIM1 and blaVIM2 metallo-beta lactamases among clinical isolates of Pseudomonas aeruginosa from Mashhad, Northeast of Iran.

Background And Objectives: The main cause of serious nosocomial infections is a Gram-negative pathogen known as Pseudomonas aeruginosa (P. aeruginosa). Carbapenems are widely used as an appropriate treatment for these infections, however resistance to these agents has been observed and is increasing.

Shear bond strength and antibacterial effects of orthodontic composite containing TiO2 nanoparticles.

Nanofillers can reduce enamel demineralization without compromising physical properties of the composite. The aim of this study was to evaluate shear bond strength (SBS) and antibacterial effects of an orthodontic composite after adding titanium oxide (TiO2) nanoparticles. Light cure orthodontic composite paste (Transbond XT) was blended with TiO2 nanoparticles.

Comparative study of the antimicrobial effect of three irrigant solutions (chlorhexidine, sodium hypochlorite and chlorhexidinated MUMS).

Aim: To compare the antimicrobial effect of 2% chlorhexidine, 2.5% sodium hypochlorite and MUMS containing 2% chlorhexidine.

Materials And Methods: All of the above irrigants were examined on Enterococcus faecalis, Streptococcus mutans, Candida albicans, Lactobacillus casei and E.