First case of disseminated phaeohyphomycosis in an immunocompetent individual due to Alternaria malorum.

A 27-year-old Iranian, previously healthy male presented with sub-cutaneous necrotic lesions with a localized dermatosis affecting the anterior chest, neck and face. These lesions consisted of singular, well-defined verrucous plaques which gradually developed and disseminated over time. The dermatosis was followed by the development of necrotic swollen lesions localized on the hard palate.

Cytokine single nucleotide polymorphisms in Iranian patients with pulmonary tuberculosis.

Background: Several genes coding for different cytokines may affect host susceptibility to tuberculosis.

Methods: In the present study, the allele and genotype frequencies of a number polymorphic genes coding for cytokines or cytokine receptors were investigated in Iranian patients with pulmonary tuberculosis (PTB).

Results: From the IL-1 cluster, a positive, significant difference was found at position -889, where the T/T genotype was over represented in PTB patients (p = 0.