Publications by authors named "Mahboobeh Erfanizadeh"
Article Synopsis
- The paraventricular nucleus of the hypothalamus (PVH) is crucial for regulating sleep and stress, and chronic REM sleep deprivation (CSD) over 21 days negatively affects its structure and function in male rats.
- In the study, rats were divided into groups receiving either curcumin or a control treatment, and their PVH was analyzed for volume, cell count, and neuron health using various scientific methods.
- Results showed that CSD led to significant decreases in PVH volume and cell numbers, along with increased neuron death, but curcumin treatment was effective in reversing these changes and restoring normal neuron arrangement.
Copper (Cu) is a vital trace element that acts as a cofactor of proteins and enzymes in many molecular pathways including the central nervous system. The accumulation or deficiency of copper could alter neuronal function and lead to neuronal degeneration and brain dysfunction. Intake of high levels of copper can also cause copper toxicosis that affects the brain structure and function.
View Article and Find Full Text PDFTransplantation of bone marrow stem cells (BMSCs) has shown to have a vital role in promoting nerve regeneration after SCI. The aim of this study was to investigate the effect of BMSCs transplantation in healing of spinal cord injury (SCI) in mice based on morphologic parameters. Forty two male mice were randomly divided into 3 groups of control with no intervention, experimental SCI without treatment, and experimental SCI transplanted with 2 × 10 BMSCs intravenously.
View Article and Find Full Text PDFBackground: In modern societies, sleep deprivation is a serious health problem. This problem could be induced by a variety of reasons, including lifestyle habits or neurological disorders. Chronic sleep deprivation (CSD) could have complex biological consequences, such as changes in neural autonomic control, increased oxidative stress, and inflammatory responses.
View Article and Find Full Text PDFBackground: Olive oil is a food additive and used in many biological studies as a solvent for other chemicals, including drugs.
Aim: The present study aimed to investigate the effects of olive oil on rats' cerebellum structure and motor function.
Materials And Methods: Male rats were randomly divided into two groups orally receiving distilled water and olive oil (1 ml/kg/day).
Objectives: To evaluate the cerebellar structure in sodium benzoate (NaB) or ascorbic acid (AA) treated rats.
Methods: This experimental study was conducted between May and September 2013 in the Laboratory Animal Center of Shiraz University of Medical Sciences, Shiraz, Iran. The rats received distilled either water, NaB (200mg/kg/day), AA (100mg/kg/day), or NaB+AA.
Sodium benzoate, a food preservative, induces anxiety and motor impairment in rats.
Neurosciences (Riyadh)
January 2014
Objective: To investigate the behavioral characteristics, including anxiety and motor impairment, in sodium benzoate (NaB) treated rats.
Methods: The study was carried out between July and September 2012 in the Laboratory Animal Center of Shiraz University of Medical Sciences, Shiraz, Iran. The rats were divided into 2 groups receiving distilled water and NaB (200mg/kg/day).