Personalized dosimetry assessment of [Lu]Lu-PSMA-617 radioligand therapy in the management of metastatic castration-resistant prostate cancer.

Introduction: Prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) is revolutionizing the treatment landscape for metastatic castration-resistant prostate cancer (mCRPC) patients. This study aimed to establish patient-specific radiation dosimetry for [Lu]Lu-PSMA-617 RLT in Iranian patients with mCRPC.

Method: Twelve biopsy-proven prostate cancer patients (aged 68.

Synthesis, Radiolabeling, and Biodistribution Study of a Novel DOTA-Peptide for Targeting Vascular Endothelial Growth Factor Receptors in the Molecular Imaging of Breast Cancer.

As angiogenesis plays a pivotal role in tumor progression and metastasis, leading to more cancer-related deaths, the angiogenic process can be considered as a target for diagnostic and therapeutic applications. The vascular endothelial growth factor receptor-1 (VEGR-1) and VEGFR-2 have high expression on breast cancer cells and contribute to angiogenesis and tumor development. Thus, early diagnosis through VEGFR-1/2 detection is an excellent strategy that can significantly increase a patient's chance of survival.

A step toward simplified dosimetry of radiopharmaceutical therapy via SPECT frame duration reduction.

Despite being time-consuming, SPECT/CT data is necessary for accurate dosimetry in patient-specific radiopharmaceutical therapy. We investigated how reducing the frame duration (FD) during SPECT acquisition can simplify the dosimetry workflow for [Lu]Lu-PSMA radioligand therapy (RLT). We aimed to determine the impact of shortened acquisition times on dosimetric precision.

Astatine-211 Radiopharmaceuticals; Status, Trends, and the Future.

The low range of alpha particles provides an opportunity to better target cancer cells theoretically leading to the introduction of interesting alpha emitter radiopharmaceuticals including Ac, Pb, etc. The combination of high energy and short range of alpha emitters differentiates targeted radiotherapy from other methods and reduces unwanted cytotoxicity of the cells around the tumoral tissue. Among interesting alpha emitters candidates for targeted therapy, At, one of the radioisotopes with the best optimal decay properties, shows great promise for targeted radiotherapy in some animal prostate cancer xenograft studies and bone micro tumors with significant effects compared to other beta and alpha emitters and also demonstrates interesting properties for clinical applications.

[F]FDG-PET/CT Radiomics and Artificial Intelligence in Lung Cancer: Technical Aspects and Potential Clinical Applications.

Lung cancer is the second most common cancer and the leading cause of cancer-related death worldwide. Molecular imaging using [F]fluorodeoxyglucose Positron Emission Tomography and/or Computed Tomography ([F]FDG-PET/CT) plays an essential role in the diagnosis, evaluation of response to treatment, and prediction of outcomes. The images are evaluated using qualitative and conventional quantitative indices.

Identifying women's needs to adjust to postpartum changes: a qualitative study in Iran.

Background: The transition to motherhood is associated with stress because of extensive and rapid changes to which women need to be able to adjust. To help women adjust to postpartum changes, their needs during this period must be identified. Therefore, the present qualitative study explored the needs of women for adjusting to postpartum changes.

Factors Affecting Women's Adjustment to Postpartum Changes: A Narrative Review.

Background: Postpartum period is associated with stress and pressure, and the woman must adjust herself to these changes. This study aimed to review the factors affecting women's adjustment to postpartum changes in conducted studies.

Materials And Methods: This review was conducted by searching databases such as ISI Web of Science, Science Direct, Scopus, Cochrane, PubMed and Scientific Information Database (SID), Iranian Medical Articles Database (IranMedex), Iranian Research Institute for Information Science and Technology (IranDoc), and the Iranian Magazine Database (MagIran), as well as searching through Google Scholar (as a Web search engine) in December 2019.

Living versus deceased kidney transplantation: Comparison of complications.

Introduction: It is assumed that the outcome of kidney transplantation from living donors is more favorable than deceased donors. However, over the years there has been an overall improvement in transplant survival from both living and deceased donors. In this article we have evaluated and compared the most recent results in living and deceased donor kidney transplantations.

Exploring the experiences related to postpartum changes: perspectives of mothers and healthcare providers in Iran.

Background: Numerous changes occur in different aspects of women's lives in the postpartum period. Women's adjusting with problems and taking advantage of this opportunity can develop their personality. In this regard, accurate knowledge of their experiences and feelings is necessary to help them to benefit from this period.

Mandibular Mass as an Only Presentation of Metatatic Renal Cell Carcinoma For Four Years: A Case Report.

Renal cell carcinoma is one of the most common tumors of the urinary tract. This tumor may appear as Para neoplasticsyndromes or distant metastasis. Metastases in uncommon areas are one of the characteristics of renal tumors.

Efficacy of communication skills training workshop on sexual function in infertile women.

Background: Sexual function is reduced in an infertile woman. This study aimed to determine the effect of a communication skills training program on sexual function in infertile women referring to the medical centers in Isfahan in 2012.

Materials And Methods: This study is a field trial study using control groups in which 32 infertile couples were selected by convenience sampling, and then, were randomly divided into control and training groups.

Incidence and complications of acute kidney injury following coronary artery bypass graft: a retrospective cohort study.

Introduction: Acute kidney injury (AKI) is a common complication of coronary artery bypass graft with several serious complications. This study aimed to find the incidence of AKI after coronary artery bypass graft and its complications based on the Acute Kidney Injury Network (AKIN) criteria.

Materials And Methods: This study was done on 3470 patients who had undergone isolated coronary artery bypass graft.

The effect of meperidine on peripartum breastfeeding and neonatal weight.

Objective: To evaluate the effect of Meperidine, commonly administered for labor analgesia, on newborn weight and peripartum breastfeeding during two months after delivery.

Materials And Methods: This pilot cohort study was conducted between October 2010 and October 2011 at the Women Hospital of the Tehran University of Medical Sciences. In this study, we examined the effects of meperidine on breastfeeding and neonatal weight.