HBeAg seroconversion in children infected during early childhood with hepatitis B virus.

Background: Seroconversion of hepatitis B e-antigen (HBeAg) to anti-HBe is associated with lower viral load and liver diseases.

Objectives: The purpose of this study was to assess the seroconversion rate of HBeAg to anti-HBe in children who acquired hepatitis B virus (HBV) infection during early childhood.

Study Design: From September 1990 to December 2010, 139 HBeAg-positive children were followed up.

Outcomes of passive-active immunoprophylaxis given to infants of mothers infected with hepatitis B virus in Babol, Iran.

Background: Infants born to chronic hepatitis B virus (HBV) infected mothers may be infected in spite of receiving passive-active immunoprophylaxis.

Objectives: The purpose of this study was to assess the outcome of infants born to women actively infected by HBV.

Study Design: From April 2004 to September 2009, infants born to women actively infected by HBV received hepatitis B immune globulin (HBIG) and the first dose of hepatitis B vaccine at birth.