Publications by authors named "Maharani R Duhita"

Diabetes is closely related to immune response problems when it occurs chronically. Pegagan () is a medicinal plant with active compounds. Madecassoside is beneficial in treating diabetes, and nanoparticle technology is expected to enhance the medicinal potential and availability of pegagan compounds.

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  • This study examines how factors like sex and oral contraceptive pill (OCP) use impact individual responses to meals with high protein content in regulating energy balance.
  • It involved 21 healthy participants (7 men, 7 women not on OCP, and 7 women on OCP) consuming isocaloric meals with different protein levels, measuring their energy expenditure (EE) and feelings of hunger and fullness.
  • Results showed men had a greater energy expenditure response to higher protein meals, while women not on OCP plateaued at lower protein levels, and OCP users felt less full after meals, indicating the need to consider personal factors in dietary interventions for weight management.
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  • The study explores how dietary protein affects energy expenditure (EE) based on menstrual cycle phases and the use of oral contraceptives in women.
  • Researchers measured EE in healthy young women—both those taking and not taking the pill—and men after consuming high-protein (HP) versus normal-protein (NP) meals.
  • Results showed that HP significantly increased EE in women not using the pill and men, but had no effect in women taking the pill, suggesting that oral contraceptive use may limit the thermogenic benefits of protein for weight control.
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Background: Recently, insulin analogs have become widely used for the treatment of diabetes. The aim of this study was to determine differences in the antigenicity of insulin analogs and long-term changes in titers in patients with type 2 diabetes.

Methods: Insulin antibodies were examined using polyethylene glycol and protein G methods in 381 patients with type 2 diabetes.

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