Replication-competent recombinant porcine reproductive and respiratory syndrome (PRRS) virus expressing antiviral cytokine interferon-ω5 as a modified live virus vaccine.

Porcine reproductive and respiratory syndrome (PRRS), caused by the highly variable PRRS virus (PRRSV), presents a significant challenge to the swine industry due to its pathogenic and economic burden. The virus evades host immune responses, particularly interferon (IFN) signaling, through various viral mechanisms. Traditional vaccines have shown variable efficacy in the field, prompting the exploration of novel vaccination strategies.

Transforming agri-food value chains in Bangladesh: A practical application of blockchain for traceability and fair pricing.

The agricultural sector is a vital component of Bangladesh's economy, but its agri-food supply chain faces signifi-cant inefficiencies primarily due to the involvement of numerous intermediaries. This complexity not only reduces the profits for farmers but also affects the overall transparency and efficiency of the supply chain. This study aims to em-ploy blockchain technology to transform the traditional agri-food supply chain in Bangladesh, focusing on increasing transparency, enhancing efficiency, and improving profitability for farmers, thus potentially bolstering the entire agri-food ecosystem in the country.

Comprehensive smartphone image dataset for bean and cowpea plant leaf disease detection and freshness assessment from Bangladesh vegetable fields.

Agriculture greatly impacts Bangladesh's economy, and vegetable cultivation plays a significant role in Agriculture by providing nourishment, and food security as well as improving the economy. The necessity of food production is growing similarly to the population growth. The farmers of Bangladesh are working hard to meet this need for food production and to gain yields.

Comprehensive smart smartphone image dataset for plant leaf disease detection and freshness assessment from Bangladesh vegetable fields.

Bangladesh's agricultural landscape is significantly influenced by vegetable cultivation, which substantially enhances nutrition, the economy, and food security in the nation. Millions of people rely on vegetable production for their daily sustenance, generating considerable income for numerous farmers. However, leaf diseases frequently compromise the yield and quality of vegetable crops.

Designing and development of efficient multi-epitope-based peptide vaccine candidate against emerging avian rotavirus strains: A vaccinomic approach.

Background: Enteric avian rotavirus (ARV) is the etiological agent of several health problems that pose a global threat to commercial chickens. Therefore, to avoid these widespread epidemics and high mortality rates, only vaccine and strict biosecurity are required.

Method: The present study employs computational techniques to design a unique multi-epitope-based vaccine candidate that successfully activates immune cells against the ARV by combining adjuvant, linker, and B and T-cell epitopes.

Smartphone image dataset to distinguish healthy and unhealthy leaves in papaya orchards in Bangladesh.

Papaya, renowned for its nutritional benefits, represents a highly profitable crop. However, it is susceptible to various diseases that can significantly impede fruit productivity and quality. Among these, leaf diseases pose a substantial threat, severely impacting the growth of papaya plants.

Clinical profile and serological correlation with haemolysis in DAT-positive autoimmune haemolytic anaemia patients in Bangladesh.

Discerning the type of autoimmune haemolytic anaemia (AIHA) is crucial for transfusion support and initiation of treatment. This study aimed to establish the clinical profile and serological character of red cell autoantibodies and to investigate the relationship with haemolysis in AIHA patients who were direct antiglobulin test (DAT)-positive. A total of 59 DAT-positive AIHA patients were included in this study.

A comprehensive dataset for sentiment and emotion classification from Bangladesh e-commerce reviews.

In the rapidly evolving domain of e-commerce, analyzing customer feedback through reviews is crucial, particularly for understanding and enhancing consumer experience in the Bangladeshi market. Our comprehensive dataset, derived from two Bangladeshi e-commerce platforms, Daraz and Pickaboo, features a diverse collection of reviews in both Bengali and English, covering a broad range of products. These reviews are not only rich in linguistic variety but also encapsulate a spectrum of emotions, some even conveyed through emojis, offering a deep dive into consumer sentiment.

ArsenicSkinImageBD: A comprehensive image dataset to classify affected and healthy skin of arsenic-affected people.

Compared to other popular research domains, dermatology got less attention among machine learning researchers. One of the main concerns for this problem is an inadequate dataset since collecting samples from the human body is very sensitive. In recent years, arsenic has emerged as a significant issue for dermatologists.

Comprehensive dataset of annotated rice panicle image from Bangladesh.

Bangladesh's economy is primarily driven by the agriculture sector. Rice is one of the staple food of Bangladesh. The count of panicles per unit area serves as a widely used indicator for estimating rice yield, facilitating breeding efforts, and conducting phenotypic analysis.

Knowledge, attitude, and practice of university students towards monkeypox in Bangladesh.

The recent outbreak of viral zoonotic disease-monkeypox-caused by the monkeypox virus, has infected many people worldwide. This study aims to explore the knowledge, attitudes, and practices (KAP) concerning monkeypox among university students in Bangladesh. Data were collected using purposive snowball sampling from 887 university students through an online survey using Google Form.

Qualitative assessment of programmatic constraints in delivery of effective interventions for improving maternal nutrition in Bangladesh.

Introduction: Maternal undernutrition is highly prevalent in most of the developing countries. Prevalence of both extremes of maternal malnutrition (undernutrition and overweight/obesity) are common in those countries. For Bangladesh, the scenario is not different.

Stool specimen for diagnosis of pulmonary tuberculosis in adults: a systematic review.

Objective: To assess the diagnostic accuracy of stool specimens to diagnose pulmonary tuberculosis (PTB) in adults.

Design: Systematic review.

Data Sources: MEDLINE (Ovid), Embase (Ovid), Web of Science and the Cochrane database were searched from inception to 9 March 2023-10 March 2023 using a comprehensive search strategy; reference lists of selected articles and relevant review articles were manually searched.

Immunogenic multi-epitope-based vaccine development to combat cyclosporiasis of immunocompromised patients applying computational biology method.

Cyclospora cayetanensis infections, also known as cyclosporiasis, persist to be the prevalent emerging protozoan parasite and an opportunist that causes digestive illness in immunocompromised individuals. In contrast, this causal agent can affect people of all ages, with children and foreigners being the most susceptible populations. For most immunocompetent patients, the disease is self-limiting; in extreme circumstances, this illness can manifest as severe or persistent diarrhea as well as colonize on secondary digestive organs leading to death.

Occupational exposure to livestock and risk of tuberculosis and brucellosis: A systematic review and meta-analysis.

Occupational diseases are caused by zoonotic pathogens, which spread to humans through various types and intensities of human-livestock contact at work. In the present era, human brucellosis and tuberculosis remain the predominant occupational diseases throughout the world. However, the actual percentage of reported cases that are acquired from various livestock-related occupational groups is not well known.

Insight into the first multi-epitope-based peptide subunit vaccine against avian influenza A virus (H5N6): An immunoinformatics approach.

The rampant spread of highly pathogenic avian influenza A (H5N6) virus has drawn additional concerns along with ongoing Covid-19 pandemic. Due to its migration-related diffusion, the situation is deteriorating. Without an existing effective therapy and vaccines, it will be baffling to take control measures.

Exploratory Algorithm of a Multi-epitope-based Subunit Vaccine Candidate Against : Reverse Vaccinology-Based Immunoinformatic Approach.

Cryptosporidiosis is the leading protozoan-induced cause of diarrheal illness in children, and it has been linked to childhood mortality, malnutrition, cognitive development, with retardation of growth. , the anthroponotically transmitted species within the genus, contributes significantly to the global burden of infection, accounting for the majority of clinical cases in numerous nations, as well as its emergence in the last decade is largely due to detections obtained through noteworthy epidemiologic research. Nevertheless, there is no vaccine available, and the only licensed medication, nitazoxanide, has been demonstrated to have efficacy limitations in a number of patient groups recognized to be at high risk of complications.

Global prevalence of zoonotic pathogens from pigeon birds: A systematic review and meta-analysis.

Pigeons have been considered the most preferred companion for human civilizations since prehistoric times. Despite the fact that pigeons offer the most palatable and nutritious food and provide pleasure to humans, they can pose a health risk because of carrying infectious and zoonotic organisms. Moreover, the scanty of systematic reports on the occurrence of zoonotic pathogens in pigeon makes the situations worst.

Seawater fungi-derived compound screening to identify novel small molecules against dengue virus NS5 methyltransferase and NS2B/NS3 protease.

Dengue fever is a virus spread by mosquitoes that has no effective treatment or vaccination. Several dengue cases combined with the current COVID-19 pandemic, exacerbates this problem. Two proteins, NS5 methyltransferase and NS2B/NS3 primary protease complexes, are crucial for dengue viral replication and are the target sites for antiviral development.

Inhibitory Potentiality of Secondary Metabolites Extracted from Marine Fungus Target on Avian Influenza Virus-A Subtype H5N8 (Neuraminidase) and H5N1 (Nucleoprotein): A Rational Virtual Screening.

Highly contagious avian influenza virus' (AIV) subtypes, including H5N1 and H5N8 are considered as serious threats for poultry industry. Despite its severity, treatment and mitigation attempts are fall into baffling. Though a few approved anti-influenza medications are available, the M2 channel blockers amantadine and rimantadine, as well as the neuraminidase inhibitor oseltamivir are being less effective due to widespread drug resistance.

A systematic review and meta-analysis on prevalence and epidemiological risk factors of zoonotic Fascioliasis infection among the ruminants in Bangladesh.

The parasitic Fascioliasis is a zoonotic and economically significant disease for livestock and humans, creating public health concerns around the world, including in Bangladesh. Populations of Bangladesh are more vulnerable to this parasitic infestation for their intimate interactions. To tackles the adverse effects on humans from food animals, it is exigency to know the exact prevalence and associated risk factors of zoonotic Fascioliasis among ruminants.

Multi-epitope based subunit vaccine construction against Banna virus targeting on two outer proteins (VP4 and VP9): A computational approach.

Recently, RNA viruses have gained a mammoth concern for causing various outbreaks, and due to pandemics, they are acquiring additional attention throughout the world. An emerging RNA as well as vector-borne Banna Virus (BAV) is a human pathogen resulting in encephalitis, fever, headache, muscle aches, and severe coma. Besides human, pathogenic BAV was also detected from pigs, cattle, ticks, midges, and mosquitoes in Indonesia, China, and Vietnam.

Changing trends in nutritional status of adolescent females: a cross-sectional study from urban and rural Bangladesh.

Objectives: Malnutrition remains a major problem among adolescents worldwide, but the types of nutritional problem impacting this group are changing significantly. This study aims to describe and analyse the trends in nutritional status and related epidemiological characteristics of 10 to 19 years old adolescent girls over time (2001 to 2018) in Bangladesh.

Methods: We extracted data from the Diarrhoeal Disease- Surveillance System of the International Centre for Diarrhoeal Disease Research Bangladesh.

Mother's dietary diversity and association with stunting among children <2 years old in a low socio-economic environment: A case-control study in an urban care setting in Dhaka, Bangladesh.

Mothers are often responsible for preparing nutritious foods in their households. However, the quality of mother's diets is often neglected, which may affect both mother's and child's nutrition. Because no single food contains all necessary nutrients, diversity in dietary sources is needed to ensure a quality diet.