Phylogenetic analysis and forensic evaluation among Rakhine, Marma, Hajong, and Manipuri tribes from four culturally defined regions of Bangladesh using 17 Y-chromosomal STRs.

We have analyzed haplotypes for 17 Y chromosomal STR loci in Bangladeshi mainstream Bengali population and four largest ethnic groups inhabiting the North-Eastern and Southern region of Bangladesh using AmpFlSTR® Yfiler® PCR amplification systems. A total of 667 haplotypes from Bangladeshi Bangali, 157 from Rakhine, 144 from Marma, 112 from Hajong, and 136 from Manipuri individuals were observed with corresponding discrimination capacity (DC) of 0.973 for Bengali, 0.

Genetic polymorphism studies on 22 autosomal STR loci of the PowerPlex Fusion System in Bangladeshi population.

Genetic polymorphism of 22 autosomal STR loci included in PowerPlex® Fusion System (D3S1358, D1S1656, D2S441, D10S1248, D13S317, Penta E, D16S539, D18S51, D2S1338, CSF1PO, Penta D, TH01, vWA, D21S11, D7S820, D5S818, TPOX, D8S1179, D12S391, D19S433, FGA and D22S1045) was studied in 188 unrelated Bangladeshi Bengali individuals. Allele frequencies and forensic efficiency parameters such as, the power of discrimination (PD), observed and expected heterozygosity (Ho & He), polymorphism information content (PIC), probability of match (PM), power of exclusion (PE) and typical paternity index was calculated for the loci. The combined PM and PE for all 22 STR loci were calculated to be 5.

Population genetics of 17 Y-chromosomal STRs loci in Garo and Santal tribal populations in Bangladesh.

Allele frequencies and haplotype diversity of 17 Y-chromosomal short tandem repeat (STR) loci included in Y-filer™ PCR amplification kit were studied in 120 Garo and 139 Santal male individuals residing in two distinct regions of Bangladesh. A total of 99 different haplotypes from Garo and 129 different haplotypes from Santal individuals were observed with a corresponding discrimination capacity (DC) of 0.825 and 0.

Allele Frequencies of 10 Autosomal STR Loci from Chakma and Tripura Tribal Populations in Bangladesh.

Allele frequencies of ten autosomal STR loci, D3S1358, vWA, D16S539, D2S1338, D8S1179, D21S11, D18S51, D19S433, TH01, and FGA were investigated in Chakma and Tripura tribal populations of Bangladesh. In both the populations, all loci were in Hardy-Weinberg equilibrium except for FGA locus in Chakma and D21S11 in Tripura. All the loci were highly polymorphic in Chakma population with an observed heterozygosity (Ho) of >0.

Forensic evaluation of STR data for the PowerPlex 16 System loci in a Bangladeshi population.

Allele frequencies of 15 autosomal STR loci included in PowerPlex 16 System were determined from a sample of 148 unrelated Bangladeshi individuals. Forensic efficiency parameters such as, the power of discrimination (PD), observed and expected heterozygosity (H), polymorphism information content (PIC), probability of match (PM), power of exclusion (PE), and typical paternity index were calculated for the loci. These parameters indicated the usefulness of the loci in paternity testing and personal identification in the Bangladeshi population.

A study on efficacy of lamivudine therapy in decompensated cirrhosis of liver due to chronic hepatitis B virus infection.

The prognosis of decompensated cirrhosis of liver resulting from chronic Hepatitis B Virus (HBV) infection is poor and liver transplantation is the only established mode of treatment. The benefits of treatment with interferon are outweighed by serious side effects and risks of fatal exacerbation of disease activity. Lamivudine rapidly reduces hepatitis B viral DNA in serum to undetectable levels.