Publications by authors named "Maham Siddiqi"

Article Synopsis
  • - A 23-year-old male experienced vision loss and eye pressure due to impending central retinal vein occlusion (CRVO), leading to the discovery of retinal hemorrhages in his left eye.
  • - Despite normal infectious and autoimmune labs, tests revealed hypercoagulable changes and increased right heart pressures, while genetic tests for clotting disorders were negative.
  • - After treatment with anticoagulation, his vision improved, suggesting that his history of vaping may have contributed to his hypercoagulable state and CRVO, highlighting the need for more research on vaping's health effects.
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Objective: Hepatic stellate cells (HSCs) contain a number of bioactive metabolites or their precursors including retinoids in their characteristic lipid droplets. The loss of lipid droplets and retinoids is a hallmark of HSC activation, but it remains unclear whether this loss promotes HSC activation, liver fibrogenesis or carcinogenesis.

Design: Spontaneous and experimental fibrogenesis as well as a diethylnitrosamine-induced hepatocarcinogenesis were investigated in lecithin-retinol acyltransferase (LRAT)-deficient mice which lack retinoid-containing lipids droplets in their HSCs.

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Background: It is often felt that developing countries need to improve their quality of healthcare provision. This study hopes to generate data that can help managers and doctors to improve the standard of care they provide in line with the wishes of the patients.

Methods: It was a cross sectional study carried out at a major tertiary care hospital of Karachi.

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Objective: To estimate the occurrence rate of sleep deprivation and to identify the environmental, staff-related and patient-related factors associated with SD among general ward patients of a tertiary care hospital in Pakistan.

Methods: In a cross-sectional study, a pre-tested questionnaire was administered to 108 patients admitted into the general medical and general surgical wards of Aga Khan University Hospital, Karachi.

Results: In all, 50 (46.

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Background: Drug abuse is hazardous and known to be prevalent among young adults, warranting efforts to increase awareness about harmful effects and to change attitudes. This study was conducted to assess the perceptions of a group of medical students from Pakistan, a predominantly Muslim country, regarding four drugs namely heroin, charas, benzodiazepines and alcohol.

Results: In total, 174 self-reported questionnaires were received (87% response rate).

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