Publications by authors named "Mahad Rehman"
(PA) is an opportunistic gram-negative pathogen that can infect the cornea, leading to permanent vision loss. Autophagy is a cannibalistic process that drives cytoplasmic components to the lysosome for degradation and/or recycling. Autophagy has been shown to play a key role in the removal of intracellular pathogens and, as such, is an important component of the innate immune response.
View Article and Find Full Text PDFObjective: To compare radiographic measurements of lateral tibial slope (LTS), medial TS (MTS), and coronal TS (CTS) in MRI-defined intact, injured, and mucoid-degenerated native ACL knees and determine inter-reader reliability.
Materials And Methods: Patient records from 2 years at tertiary care hospitals were reviewed for individuals aged 18-100 undergoing 3-Tesla knee MRI and radiographs. Two randomly selected cohorts, control, and pathologic ACLs on MRI with 86 patients each, were age, gender, and BMI-matched.
(PA) is a gram-negative opportunistic pathogen that can infect the cornea as a result of trauma or contact lens wear. In addition to their known energy producing role, mitochondria are important mediators of immune signaling and host defense. While certain pathogens have developed strategies to evade host defenses by modulating host mitochondrial dynamics and metabolism, the ability of PA to harness host cell mitochondria during corneal infection is unknown.
View Article and Find Full Text PDFIntroduction: The underrepresentation of underrepresented minorities (URMs) in the medical field, particularly in ophthalmology, poses a critical challenge to achieving diversity and equity. While URMs constitute 19% of medical school attendees, their presence is markedly lower in ophthalmology residency programs and among practicing ophthalmologists. This study seeks to investigate the prevalence of diversity statements on ophthalmology residency program websites and their role in the underrepresentation of URMs within the field.
View Article and Find Full Text PDFIntroduction: Large language models (LLMs) have transformed various domains in medicine, aiding in complex tasks and clinical decision-making, with OpenAI's GPT-4, GPT-3.5, Google's Bard, and Anthropic's Claude among the most widely used. While GPT-4 has demonstrated superior performance in some studies, comprehensive comparisons among these models remain limited.
View Article and Find Full Text PDFArticle Synopsis
- This study explored how visceral and subcutaneous body fat affect 3D imaging in patients with greater trochanteric pain syndrome (GTPS) compared to those with osteoarthritis (OA).
- The research involved evaluating 93 patients, matched for age and sex, assessing their fat distribution using CT scans, but found no significant differences in fat measurements between the two groups.
- The findings suggest that being overweight or obese may not directly cause GTPS, leading to the hypothesis that other conditions, like gluteal tendinopathy or bursitis, may play a more important role in its development.
Article Synopsis
- This systematic review investigates the effectiveness of MRI, ultrasonography, and radiography in diagnosing posterior tibial tendon dysfunction (PTTD) by analyzing studies from various medical databases up to April 2023.
- Out of 634 initial studies, 12 were included, revealing that MRI offers the highest sensitivity (up to 95%) and specificity (up to 100%) for detecting PTT tears, making it superior to ultrasound and radiography in diagnostic accuracy.
- Though MRI is preferred for precise diagnosis, ultrasound and radiographs may still be utilized due to their accessibility and cost-effectiveness, addressing the needs of the 3% of women over 40 and 10% of adults over 65 affected by PTTD