Publications by authors named "Maha H Morsi"

Lung cancer remains a major global health challenge, contributing to substantial morbidity and mortality rates. Nintedanib, a tyrosine kinase inhibitor, has demonstrated potential as a treatment for lung cancer. We aim to evaluate nintedanib's efficacy in treating patients with non-small cell lung cancer (NSCLC), depending on the available evidence.

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Background: Prostate cancer (PC) is responsible for large numbers of cancer-related deaths in males worldwide, and it has been linked to an increase in cardiovascular morbidity and mortality (CVM). The purpose of this research is to identify the incidence and risk factors for CVM in PC patients.

Methods: In this retrospective cohort study, we collected data from patients with PC diagnosed between 2000 and 2014 from the Surveillance, Epidemiology, and End Results (SEER) database.

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Melamine (ML) is a common environmental contaminant, commonly used in food fraud, representing a serious health hazard and jeopardizing human and animal health. Recently, nootkatone (NK), a naturally occurring sesquiterpenoid, has garnered considerable attention due to its potential therapeutic advantages. We investigated the potential mechanisms underlying the protective effects of NK against ML-induced liver injury in rats.

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Article Synopsis
  • Systemic sclerosis (SSc) is an autoimmune disorder that primarily affects the lungs and skin, leading to complications like vasculopathy; this study investigates the role of anti-vinculin antibodies in diagnosing SSc and comparing levels between different patient populations.
  • The study involved 140 participants split into three groups: PAH-predominant, ILD-predominant, and a control group, with findings showing significantly higher anti-vinculin antibody levels in SSc patients compared to controls.
  • Results indicate that anti-vinculin antibodies could serve as diagnostic biomarkers for scleroderma, particularly highlighting differences between PAH and ILD patient populations in the presence of these antibodies.
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Background: The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been predominantly linked to respiratory distress syndrome, but hepatic injury has also been reported. The mechanism of liver injury is poorly understood.This review aimed to systematically review the current data through laboratory tests and liver tissue pathology to ascertain the correlation of liver involvement in SARS-CoV-2 infection patients.

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