Prevalence of Polypharmacy and Factors Associated with it Among Saudi Older Adults - Results from the Saudi National Survey for Elderly Health (SNSEH).

Background And Objectives: The percentage of Saudi older adults (SOA) is increasing over time. With advanced age, the prevalence of chronic diseases and multiple disabilities are increasing. This leads to increase utilization of multiple medications.

Estimation of Tacrolimus Clearance in Saudi Adult Kidney Transplant Recipients.

Tacrolimus is commonly used in adult kidney transplant patients. Only few studies have so far described the pharmacokinetics of tacrolimus in the Saudi population. Thus, the goal of this study is to determine the population pharmacokinetics of tacrolimus in Saudi adult kidney transplant recipients and to identify the factors that explain variability.

An update on the potential role of intestinal first-pass metabolism for the prediction of drug-drug interactions: the role of PBPK modeling.

The intestinal absorption process is a combination of several events that are governed by various factors. Several transport mechanisms are involved in drug absorption through enterocytes via active and/or passive processes. The transported molecules then undergo intestinal metabolism, which together with intestinal transport may affect the systemic availability of drugs.

Patients' understanding of prescription drug label instructions in developing nations: The case of Saudi Arabia.

Background: Processing health-related data is challenging for patients. It is believed that low education level and low socioeconomic status are associated with prescription label misunderstanding, which may lead to poor clinical outcomes, increased adverse drug reactions, and increased health costs.

Objectives: The aim of this study was to gain a better insight into the current understanding of prescription drug labels, and to determine the main factors affecting patients' understanding of prescription labels.