Two-bed SPECT/CT versus planar bone scintigraphy: prospective comparison of reproducibility and diagnostic performance.

Objective: To evaluate the reproducibility and diagnostic performance of two-bed single-photon emission computed tomography/computed tomography (SPECT/CT) images (TBSCT), compared to conventional planar bone scintigraphy (PBS) for the diagnosis of osseous metastasis.

Methods: Patients with known solid tumor, referred to perform PBS, were included in this prospective study. PBS acquisition was followed by TBSCT images, covering at least the chest, abdomen and pelvis.

Influence of low grade exercise on skeletal scintigraphy using Tc-99m methylene diphosphonate.

Background: Tc-99m methylene diphosphonate [MDP] bone scan is the basis of the skeletal imaging in nuclear medicine being a highly sensitive tool for detecting bone diseases. Mechanical stimulation induced by low grade exercise or whole-body vibration appears to be advantageous regarding the maintenance and/or improvement of skeletal mass in humans. We aimed to assess the physiological influence of low grade exercise on the quality of skeletal scintigraphy using Tc-99m MDP.

Response rate and factors affecting the outcome of a fixed dose of RAI-131 therapy in Graves' disease: a 10-year Egyptian experience.

The aim of this study was to evaluate response and compare the success rate of two different doses of iodine-131 ((131)I) therapy in the treatment of Graves' disease and investigate the factors that may affect outcome. A retrospective analysis was carried out on 321 patients treated with (131)I for Graves' disease. Group 1 (155 patients) received 8 mCi and group 2 (166 patients) received 12 mCi.