Publications by authors named "Mah Rukh Nisar"
A 60-year-old man with a history of diabetes mellitus and hypertension presented with diplopia and vertigo for two days. These symptoms had a gradual onset, were progressive, and were associated with a headache that had been present for 15 days. His blood sugar level was 376 mg/dl.
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- Hepatorenal syndrome (HRS) is a serious condition linked to advanced liver disease, characterized by a rapid decline in kidney function, with high mortality rates despite recent treatment advancements.
- A meta-analysis of 29 studies, selected from over 8,000, showed that vasoconstrictor agents like terlipressin can improve kidney function and reduce the need for dialysis but do not significantly lower mortality rates.
- The findings suggest that while vasoconstrictors are beneficial for managing HRS, there is a clear need for personalized treatment plans and further research to identify more effective therapies that improve survival outcomes without increasing side effects.
The human gut microbiota (GM) might play a significant role in the development or remission of metabolic syndrome (MetS) and associated disorders. Contributing factors include diets rich in unhealthy, processed foods that contain preservatives, emulsifiers, and stabilizers. Diet influences the GM's composition, diversity, and species richness in a time-dependent manner.
View Article and Find Full Text PDFEndoscopic cholangiopancreatography (ERCP) is a widely used diagnostic and therapeutic tool for pancreaticobiliary conditions. One of its major complications is pancreatitis. This study aims to understand the incidence of post-ERCP pancreatitis after using rectal diclofenac and Indomethacin as prophylactic measures.
View Article and Find Full Text PDFAutoimmune thyroid diseases (AITDs) pose significant challenges in clinical practice, representing one of the most common endocrine abnormalities. Vitamin D deficiency has been linked as one of the contributing factors to the etiology of AITDs. This systematic review evaluates the effects of vitamin D supplementation on thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroxine (T4) levels in adults with AITDs.
View Article and Find Full Text PDFMigraine causes debilitating headaches and significantly impacts quality of life. Effective migraine-specific treatments have been lacking until the advent of monoclonal antibodies (mAbs) targeting calcitonin gene-related peptide (CGRP) receptors, which have expanded therapy options for migraine treatment. This study explores the short- and long-term efficacy and safety of erenumab in migraine treatment.
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