Effect of a high-fat diet on the rat bladder wall and bioactive action of Brazil nut oil.

High-fat diet-induced obesity is associated with metabolic disorders. The Brazil nut has bioactive substances and has been used to control the damage caused by obesity in several organs. The work intended to show the damage caused by high-fat diet in the bladder wall and if the Brazil nut oil added to the diet could ameliorate or reverse this effect.

Short term low-calorie diet improves insulin sensitivity and metabolic parameters in obese women.

Obesity and insulin resistance are associated with an increase of cardiovascular risk factors, including adipocytokines. The aim of this study was to investigate the effect of low-calorie diet on serum lipids, adipokines, insulin resistance and body composition in obese women. It was a clinical trial with class I obese women aged 30-45 years submitted to hypocaloric diet for 90 days.

Adipocyte morphology and leptin signaling in rat offspring from mothers supplemented with flaxseed during lactation.

Objective: We have recently shown that maternal flaxseed supplementation during lactation induces insulin resistance in adult offspring. Here, we studied the effects of maternal dietary flaxseed during lactation on adipocyte morphology and leptin signaling in the hypothalamic-pituitary-thyroid axis as well as on behavioral traits in the adult progeny.

Methods: Lactating rats were fed a control (C) diet or a diet with 25% flaxseed (F).

Flaxseed supplementation of rats during lactation changes the adiposity and glucose homeostasis of their offspring.

Aims: The aim of this paper was to evaluate the effects of maternal dietary flaxseed during lactation on endocrine and metabolic factors in the adult offspring.

Main Methods: Lactating rats were divided into: (1) Controls (C), diet containing 20% casein; (2) Flaxseed (F), diet with additional 25% of flaxseed, containing 18.9% protein (13.