Natural Language Processing to Extract Meaningful Information from a Corpus of Written Knowledge in Breast Cancer: Transforming Books into Data.

Introduction: Books and papers are the most relevant source of theoretical knowledge for medical education. New technologies of artificial intelligence can be designed to assist in selected educational tasks, such as reading a corpus made up of multiple documents and extracting relevant information in a quantitative way.

Methods: Thirty experts were selected transparently using an online public call on the website of the sponsor organization and on its social media.

Should Acellular Dermal Matrices Be Used for Implant-based Breast Reconstruction after Mastectomy? Clinical Recommendation Based on the GRADE Approach.

Unlabelled: Acellular dermal matrices (ADMs) entered the market in the early 2000s and their use has increased thereafter. Several retrospective cohort studies and single surgeon series reported benefits with the use of ADMs. However, robust evidence supporting these advantages is lacking.

Evaluation of word embedding models to extract and predict surgical data in breast cancer.

Background: Decisions in healthcare usually rely on the goodness and completeness of data that could be coupled with heuristics to improve the decision process itself. However, this is often an incomplete process. Structured interviews denominated Delphi surveys investigate experts' opinions and solve by consensus complex matters like those underlying surgical decision-making.

Processing methods for human amniotic membrane as scaffold for tissue engineering with mesenchymal stromal human cells.

Tissue engineering is an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function. The aims of this work were to compare chemically and physically processed human Amniotic Membranes (hAM) and analyze the cytocompatibility and proliferation rate (PR) of two primary human mesenchymal stromal cell lines, from different sources and donor conditions seeded over these scaffolds. The evaluated hAM processes were: cold shock to obtain a frozen amniotic membrane (FEAM) with remaining dead epithelial cells, denudation of hAM with trypsin for 20/10 min (DEAM20/10) or treatment with sodium dodecyl sulfate to decellularized hAM (DAM).

Text mining and word embedding for classification of decision making variables in breast cancer surgery.

Introduction: Decision making in surgical oncology of the breast has increased its complexity over the last twenty years. This Delphi survey investigates the opinion of an expert panel about the decision making process in surgical procedures on the breast for oncological purposes.

Methods: Twenty-seven experts were invited to partake into a Delphi Survey.

The Impact of the COVID-19 Pandemic on Surgical Management of Breast Cancer: Global Trends and Future Perspectives.

Introduction: The rapid spread of COVID-19 across the globe is forcing surgical oncologists to change their daily practice. We sought to evaluate how breast surgeons are adapting their surgical activity to limit viral spread and spare hospital resources.

Methods: A panel of 12 breast surgeons from the most affected regions of the world convened a virtual meeting on April 7, 2020, to discuss the changes in their local surgical practice during the COVID-19 pandemic.

Skeletal morphogenesis of the vertebral column of the miniature hylid frog Acris crepitans, with comments on anomalies.

Although the vertebral columns of anurans have received much study in the last 150 years, few detailed descriptions exist of the skeletal morphogenesis of this anatomical unit. Herein, the ontogeny of the vertebral skeleton of the hylid frog Acris crepitans is described based on cleared and double-stained specimens, radiographs, and 3D reconstructions generated from synchrotron microCT scans. The adult axial formula is 1-7-1-1, and the vertebral centra are epichordal and procoelous.

Skeletal morphology and development of the olfactory region of Spea (Anura: Scaphiopodidae).

The nasal capsules of anurans are formed by an intricate set of sac-like cavities that house the olfactory organ and constitute the beginning of the respiratory system. In tadpoles, nasal capsules do not have a respiratory function, but each is composed of a single soft tissue cavity lined with olfactory epithelium. Our study has revealed that in Spea the nasal cartilages and septomaxillae are de novo adult structures that form dorsal to the larval skeleton of the ethmoid region.

An anatomical ontology for amphibians.

Herein, we describe our ongoing efforts to develop a robust ontology for amphibian anatomy that accommodates the diversity of anatomical structures present in the group. We discuss the design and implementation of the project, current resolutions to issues we have encountered, and future enhancements to the ontology. We also comment on future efforts to integrate other data sets via this amphibian anatomical ontology.

A general recurrent neural network approach to model genetic regulatory networks.

There is an urgent need for tools to unravel the complex interactions and functionalities of genes. As such, there has been much interest in reverse-engineering genetic regulatory networks from time series gene expression data. We use an artificial neural network to model the dynamics of complicated gene networks and to learn their parameters.

Skeletal morphology and postmetamorphic ontogeny of Acris crepitans (Anura: Hylidae): a case of miniaturization in frogs.

Acris crepitans is a small, semiaquatic member of the treefrog family Hylidae. Much recent attention has been paid to this species because of reports of population declines and malformations, yet few works have considered the skeletal anatomy of this common North American frog. Herein, we provide a detailed description of the morphology and adult ontogeny of the skeleton of A.

Skeletal development of the Mexican spadefoot, Spea multiplicata (Anura: Pelobatidae).

The larval chondrocranium of Spea multiplicata is described, as is the development and adult morphology of the skeleton. There are major modifications to the larval chondrocranium throughout development, including the presence of embryonic trabeculae in young tadpoles and significant reorganization of cartilaginous structures at metamorphosis. The first bone to ossify is the parasphenoid (Stage 35), followed by the presacral neural arches, ilium, and femur (Stage 36).

Nitrincola lacisaponensis gen. nov., sp. nov., a novel alkaliphilic bacterium isolated from an alkaline, saline lake.

A novel alkaliphilic bacterium, strain 4CAT, was isolated from decomposing wood taken from the shore of Soap Lake, a saline, alkaline lake in Grant County, WA, USA. Cells of the isolate were Gram-negative, asporogenous, short, motile rods that utilized only a limited range of organic acids as sole carbon and energy sources. In addition to oxygen, the strain possessed the ability to reduce in the presence of acetate.

Ontogeny of the bizarre: an osteological description of Pipa pipa (Anura: pipidae), with an account of skeletal development in the species.

The adult osteology of the direct-developing pipid frog, Pipa pipa, is described based on cleared-and-stained and dry skeletal specimens. Observations on skeletal development are based on cleared-and-stained embryos and young removed from the backs of preserved females. Osteologically, P.

Osteology and skeletal development of Discoglossus sardus (Anura:Discoglossidae).

Although frogs in the archaeobatrachian family Discoglossidae are reasonably well known, descriptions of their larval skeletons and osteogenesis are almost nonexistent. Skeletogenesis, chondrocranial development, and the adult skeleton of Discoglossus sardus are described on the basis of cleared and stained, dry, and radiographed specimens. In D.

[Changes in insulin (IRI) and NEFA levels in diabetic subjects after acute intravenous glipizide and tolbutamide administration].

Glypizide and i.v. tolbutamide were administered to a series of diabetics.