Publications by authors named "Maggie Ducote"
Article Synopsis
- Endometrial cancer (EC) is closely linked to obesity, particularly affecting young women, and identifying it early can improve treatment options, especially for those with severe obesity undergoing metabolic/bariatric surgery.
- A screening program using a modified questionnaire, called Modified SAMANTA, was implemented to identify women with abnormal or postmenopausal uterine bleeding (APUB) before their surgery to check for possible underlying endometrial issues.
- Over a study period from March 2021 to May 2023, nearly half of the 1371 women screened were found to have APUB, with higher prevalence linked to factors like increased BMI and certain racial demographics, highlighting the need for careful monitoring in these patients.*
Glucocorticoids (GCs) are heavily prescribed to control inflammation in various human diseases; however, side effects associated with GCs are well documented and lead to serious metabolic and immunological complications with long-term use. The paradigm for GC function includes two well described modes of activity: dimer formation of the glucocorticoid receptor (GR) promotes transactivation, while monomeric interaction with co-regulators promotes transrepression. Previously, a set of aryl pyrazole-derived glucocorticoid receptor agonists (APGRAs) with potency rivaling current commercially available glucocorticoids were described.
View Article and Find Full Text PDF