Publications by authors named "Magee G"

Objective: The thoracic branch endoprosthesis (TBE) (W.L. Gore) offers an off-the-shelf single option for thoracic endovascular aortic repair (TEVAR) of aortic arch pathology with sealing in zones 0 to 2.

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  • - Venetoclax is an effective treatment for chronic lymphocytic leukemia (CLL) that can lead to long-lasting remissions but carries a risk of tumor lysis syndrome (TLS), which necessitates careful monitoring during treatment.
  • - A study at Levine Cancer Institute examined 73 patients with CLL on venetoclax to determine how often TLS monitoring led to interventions, finding that strict adherence to monitoring occurred in 66% of cases.
  • - Results showed a low incidence of TLS, with only one laboratory case reported and no clinical cases, indicating that most patients, especially those with low tumor burden, required few interventions.
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Purpose: Despite advances in complex endovascular aortic repair techniques, spinal cord ischemia (SCI) remains a devastating complication following endovascular thoracoabdominal aortic repairs. Novel strategies to preserve key intercostal/lumbar arteries have been described. We report our early results of patients who underwent direct intercostal/lumbar artery revascularization using endovascular incorporation of fenestrations/branches or extra-anatomic approaches for fenestrated-branched endovascular aortic repairs (FBEVARs).

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  • Spinal cord ischemia (SCI) poses significant risks during endovascular aortic aneurysm repair (EVAR), even though these procedures are less invasive than open surgery, necessitating strategies to maintain spinal cord blood flow.
  • The study involved 16 EVAR cases across 15 patients, examining levels of oxidative stress and inflammatory markers before and after the procedures to understand their relationship to delayed SCI.
  • Results showed a notable increase in the oxidative stress marker 8-OHdG at 48 hours post-procedure, highlighting its potential role in predicting SCI following EVAR.
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  • Anemia is common in patients with peripheral vascular disease and can lead to serious complications and increased mortality after surgeries; transfusions, while sometimes necessary, are linked to their own risks, including infections and heart issues.
  • This study analyzed data from the Society for Vascular Surgery Vascular Quality Initiative to determine how blood transfusions affect major adverse cardiac events (MACE) and major adverse limb events (MALE) in patients undergoing lower extremity bypass operations between 2003 and 2020.
  • Results showed that patients with more severe anemia had higher rates of MACE and MALE, and the study evaluated the outcomes based on whether or not those patients received blood transfusions. *
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  • The study evaluates the safety and effectiveness of combining Iliac Branch Endoprosthesis (IBE) with physician-modified fenestrated branched endovascular aortic repair (PM-FBEVAR) for treating complex abdominal and thoracoabdominal aortic aneurysms (cAAA and TAAA) associated with iliac artery aneurysms (IAA).
  • A retrospective review of 183 patients who underwent PM-FBEVAR was conducted from 2015 to 2021, comparing outcomes between those treated with and without IBE, focusing on complications such as pelvic ischemia and technical success rates.
  • Results indicated that there were no incidences of pelvic ischemia in the IBE group,
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Objective: Fenestrated-branched endovascular aortic repair (FB-EVAR) has shown favorable outcomes for repair of complex aneurysms and thoracoabdominal aortic aneurysms. Physician-modified endografting (PMEG) and the Gore thoracoabdominal multibranch endoprosthesis (TAMBE) provide custom and off-the-shelf devices for FB-EVAR, respectively. This study compares the outcomes of TAMBE and PMEG at a single institution.

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Background: Physician modified endografts (PMEGs) have been widely used in the treatment of complex abdominal aortic aneurysm and thoracoabdominal aortic aneurysm, however, previous data are limited to small single center studies and robust data on safety and effectiveness of PMEGs are lacking. We aimed to perform an international multicenter study analyzing the outcomes of PMEGs in complex abdominal aortic aneurysms and thoracoabdominal aortic aneurysms.

Methods: An international multicenter single-arm cohort study was performed analyzing the outcomes of PMEGs in the treatment of elective, symptomatic, and ruptured complex abdominal aortic aneurysms and thoracoabdominal aortic aneurysms.

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  • - The study focuses on penetrating cerebrovascular injuries (PCVI) and their management, analyzing data from a trauma registry over a decade to evaluate patient outcomes at a trauma center mainly managed by trauma surgeons.
  • - Among 54 patients analyzed, the in-hospital stroke rate was 17%, with a mortality rate of 26%. Different treatment methods showed varying outcomes in stroke and mortality rates: arterial repair had a 30% stroke rate, ligation or embolization had 0%, and temporary intravascular shunting had an alarming 80% stroke rate.
  • - The findings highlight significant differences in complications based on the type of intervention, emphasizing that arterial repair had the best outcomes, while ligation or embolization and temporary shunting
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Objective: The Global Registry for Endovascular Aortic Treatment (GREAT) is an International prospective multicenter registry collecting real-world data on performance of Gore aortic endografts. The purpose was to analyze the long-term outcomes and patient survival rates, as well as device performance in patients undergoing thoracic endovascular aortic repair for acute and chronic and complicated or uncomplicated type B aortic dissection (TBAD).

Methods: From August 2010 to October 2016, 5014 patients were enrolled in the GREAT registry.

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Objective: Transcarotid artery revascularization (TCAR) offers a safe alternative to carotid endarterectomy (CEA), but severe calcification is currently considered a contraindication in carotid artery stenting. This study aims to describe the safety and effectiveness of TCAR with intravascular lithotripsy (IVL) in patients with traditionally prohibitive calcific disease.

Methods: All consecutive patients who underwent TCAR+IVL from 2018-2022 at nine institutions were identified.

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  • The study focuses on the technical aspects of thoracic endovascular aortic repair (TEVAR) for acute type B aortic dissection (TBAD), examining the effects of proximal and distal seal zones, left subclavian artery (LSA) revascularization, and lumbar drainage on outcomes like spinal cord ischemia (SCI) and the need for reintervention.
  • Researchers analyzed data from 583 patients who underwent TEVAR, looking at various outcomes including stroke and retrograde type A dissection while comparing different conditions of proximal seal zone (PSZ) and distal seal zone (DSZ).
  • The results indicated that while PSZ 2 might lead to higher reintervention rates, it
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Background: Disruption score (DS) is a novel bibliometric created to identify research that shifts paradigms, which may be overlooked by citation count (CC). We analyzed the most disruptive, compared to the most cited, literature in vascular surgery, and hypothesized that DS and CC would not correlate.

Methods: A PubMed search identified vascular surgery publications from 1954 to 2014.

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Background: This study examined the efficacy of an interdisciplinary limb preservation service (LPS) in improving surgical outcomes for diabetic foot ulcer (DFU) patients compared to traditional care.

Methods: Data from January 1, 2017 to September 30, 2020 were retrospectively reviewed. An interdisciplinary LPS clinic began on August 1, 2018, coexisting with a preexisting single specialty service.

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Fenestration of the septum between the true and false lumen might be necessary after aortic dissection. We report the technical aspects of in situ laser fenestration of the aortic dissection septum. Two illustrative cases are provided: a 56-year-old man with false lumen deployment of a frozen elephant trunk graft, and a 67-year-old man who underwent fenestrated endovascular aortic repair with a target branch vessel off the false lumen.

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Objective: To evaluate the cost-effectiveness of dehydrated human amnion/chorion membrane (DHACM) in Medicare enrolees who developed a venous leg ulcer (VLU).

Method: This economic evaluation used a four-state Markov model to simulate the disease progression of VLUs for patients receiving advanced treatment (AT) with DHACM or no advanced treatment (NAT) over a three-year time horizon from a US Medicare perspective. DHACM treatments were assessed when following parameters for use (FPFU), whereby applications were initiated 30-45 days after the initial VLU diagnosis claim, and reapplications occurred on a weekly to biweekly basis until completion of the treatment episode.

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Background And Objectives: Cervical spinal cord injury results in devastating loss of function. Nerve transfers can restore functional use of the hand, the highest priority function in this population to gain independence. Transfer of radial nerve branches innervating the supinator to the posterior interosseous nerve (SUP-PIN) has become a primary intervention for the recovery of hand opening, but few outcome reports exist to date.

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  • The STABILISE technique is used for treating type B aortic dissections and has shown good results, but carries risks of severe complications.
  • A specific case was reported where a patient experienced an infrarenal aortic rupture during the procedure due to balloon molding.
  • Healthcare providers are advised to exercise caution and use a smaller semi-compliant balloon to reduce the risk of such ruptures when applying the STABILISE technique.
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Introduction: Frailty, a predictor of poor outcomes, has been widely studied as a screening tool in surgical decision-making. However, the impact of frailty on the outcomes after fenestrated-branched endovascular aortic repairs (FBEVARs) is less well established. In addition, the changes in frailty during recovery after FBEVAR are unknown.

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