We herein report the synthesis of monoclinic calcium aluminate (CaAlO) nanoparticles via a facile auto-combustion method followed by calcination. We performed the auto-combustion method using aluminium nitrate and calcium nitrate as oxidants and different fuels as reductants such as urea, glycine, and a mixture of urea and glycine, with various fuel-to-oxidant equivalence ratios . Then, the combusted samples were calcined at different temperatures; 600 and 800 °C.
View Article and Find Full Text PDFBackground: Regorafenib is a multi-kinase inhibitor approved for treatment of refractory advanced colorectal cancer. It was found in the clinical trials to have a modest benefit and significant toxicity. Our aim was to assess the outcome in our local clinic practice.
View Article and Find Full Text PDFAims And Background: K-ras gene mutations contribute to the pathogenesis of colorectal cancer. We characterized K-ras mutations in colorectal tumors in patients in the Kingdom of Saudi Arabia, in terms of geographic area, age, gender, histology, stage, and anatomical localization.
Methods: Medical records and paraffin-embedded tumor samples from 150 consecutive patients with histologically proven colorectal adenocarcinoma referred to two centers in Saudi Arabia were analyzed using an LCD-array kit.