Thrust system, flower structures and transpressive duplexes in Zeidun-Kareim Belt, Central Tectonic Province, Egyptian Nubian Shield (East African Orogen).

In this study, we explore thrust system, flower structures and transpressive duplexes in the Zeidun-Kareim belt (ZKB) in the Egyptian Nubian Shield (ENS; northwestern ANS). Filed observations and the measured stretched lineations along thrust planes reveal two main thrusting directions; ESE- (to NE- and NNE-)- and NW- (to WNW-)-directions belonging to two main phases of contraction. The timing of both phases is indirectly constrained.

Mitigating diabetes-related complications: Empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats.

Background: Type 2 diabetes is one of the most prevalent chronic diseases worldwide, significantly impacting patients' quality of life. Current treatment options like metformin (MET) effectively counteract hyperglycemia but fail to alleviate diabetes-associated complications such as retinopathy, neuropathy, nephropathy, hepatopathy, and cardiovascular diseases.

Aim: To propose the supplementation of cholecalciferol (CHO) and taurine (TAU) to enhance MET efficacy in controlling diabetes while minimizing the risk of associated complications.