Serum tryptase level and inflammatory markers in exhaled breath condensate of children with exercise-induced symptoms.

Background: The pathogenesis of exercise-induced bronchoconstriction (EIB) is poorly understood.

Objective: To evaluate the biomarkers concentration in exhaled breath condensate (EBC) in schoolchildren with postexercise symptoms. We also evaluated changes in fractional exhaled nitric oxide (FeNO) value and the serum tryptase level after exercise.

Food allergy is associated with recurrent respiratory tract infections during childhood.

Introduction: To find out whether children with food allergy have an increased risk of recurrent upper and lower respiratory tract infections and of asthma.

Aim: To describe the clinical profile of children diagnosed with food allergy referred to the Allergy Clinic.

Material And Methods: We conducted a retrospective study to assess the patients' demographic, anthropometric and clinical data.

Methacholine challenge testing is superior to the exercise challenge for detecting asthma in children.

Background: Exercise-induced bronchoconstriction occurs in a large proportion of children with asthma.

Objective: To compare the predictive value of methacholine challenge testing (MCCT) and the exercise treadmill challenge (ETC) for detecting asthma in children with postexercise symptoms.

Methods: This was a prospective study of children 10 to 18 years old with postexercise symptoms.

Do children with stable asthma benefit from addition of montelukast to inhaled corticosteroids: randomized, placebo controlled trial.

Background: To determine the effects of montelukast added to maintenance inhaled steroids (ICS) therapy during the school year in children with stable asthma on the ICS use, frequency of exacerbations, lung function, asthma symptoms, fractional exhaled nitric oxide (FeNO) level and exercise-induced bronchoconstriction (EIB).

Methods: Seventy six asthmatic children aged 6-14 years, allergic to house dust mites were randomized to a double-blinded trial comparing montelukast therapy to a matching placebo. We studied following end-points: the reduction in the ICS dose, the frequency of exacerbations, lung function, asthma control test score, and the change from baseline in FEV1 during a standardized exercise treadmill challenge.