Sexual dysfunction in Huntington's Disease - a systematic review.

Introduction: Huntington's Disease (HD) is a neurodegenerative disorder of which the main symptoms are motor, cognitive and behavioural problems sometimes including sexual dysfunction.

Aim: To review the current knowledge on sexual dysfunction in HD.

Methods: Databases of Pubmed and Scopus were searched.

Roxithromycin-loaded lipid nanoparticles for follicular targeting.

Particulate drug carriers e.g. nanoparticles (NPs) have been shown to penetrate and accumulate preferentially in skin hair follicles creating high local concentration of a drug.

An extreme biomimetic approach: hydrothermal synthesis of β-chitin/ZnO nanostructured composites.

β-Chitinous scaffolds isolated from the skeleton of marine cephalopod Sepia officinalis were used as a template for the in vitro formation of ZnO under conditions (70 °C) which are extreme for biological materials. Novel β-chitin/ZnO film-like composites were prepared for the first time by hydrothermal synthesis, and were thoroughly characterized using numerous analytical methods including Raman spectroscopy, HR-TEM and XRD. We demonstrate the growth of hexagonal ZnO nanocrystals on the β-chitin substrate.

Physicochemical and electrokinetic properties of silica/lignin biocomposites.

A new method of synthesis of novel composites obtained from silica and Kraft lignin has been proposed. Silica used in the study was obtained by three methods (hydrolysis and condensation of tetraethoxysilane, precipitation in a nonpolar and polar medium with the use of sodium silicate). To extend the possible range of applications, the silica was preliminary modified with N-2-(aminoethyl)-3-aminopropyltrimethoxsysilane, and finally it was modified with Kraft lignin earlier oxidised with sodium periodate (lignin bonded to SiO2 by covalent interactions).

Electrokinetic and bioactive properties of CuO∙SiO2 oxide composites.

CuO∙SiO(2) hybrid oxide precipitated on a semi-technical scale was thoroughly characterised in terms of physicochemical properties. Its particle size distribution and SEM analysis were performed to establish dispersion and surface morphology. Chemical analysis provided information on the content of CuO and SiO(2) oxides in the hybrid systems.

Comparison of silica gel modified with three different functional groups with C-18 and styrene-divinylbenzene adsorbents for the analysis of selected volatile flavor compounds.

A comparison of SPE cartridges produced in authors laboratory containing silica modified by addition of three functional moieties with standard C-18 and SDVB cartridges was made in terms of their applicability for the isolation of flavor compounds. Compounds found in wine and grapes were used for model mixture, which was spiked into a grape juice. Functionalized phases for SPE were prepared modifying silica gel with alkoxysilanes with different functional groups: (3-(phenylamino)-propyltrimethoxysilane, octyltriethoxysilane and octadecyl-silane.