Publications by authors named "Magdalena M Shtetinska"
Nucleic Acids Res
July 2024
Article Synopsis
- - Protein-protein interaction experiments often produce false positives, but the new WeSA (Weighted SocioAffinity) metric helps to differentiate genuine interactions from noise by analyzing large datasets like IntAct and BioGRID.
- - WeSA has been shown to improve accuracy in determining interaction confidence, achieving high scores in ROC analysis with results indicating high true positive rates and precision rates (AUC = 0.93, TPR = 0.84, FPR = 0.11, Precision = 0.98).
- - The WeSA web server is user-friendly and allows researchers to submit their own data or explore existing human protein interaction information, with results displayed in tables and network visualizations to easily identify and remove false positives
