Drugs of abuse in wastewater and suspended particulate matter--further developments in sewage epidemiology.

This manuscript reports, for the first time, a monitoring study analysing wastewater and associated suspended particulate matter (SPM) to determine the concentration of drugs of abuse and metabolites in wastewater influent. The monitoring of SPM is crucial for target analytes because, depending on their physico-chemical properties, they may partition to particulates; thus, analysis of wastewater only will result in under-reporting of the concentration of target analytes in the sample. A daily one week monitoring study was carried out at a WWTP serving one of the largest cities in the Czech Republic; representing the first comprehensive application of the sewage epidemiology approach in the Czech Republic.

Application of different extraction methods for the determination of selected pesticide residues in sediments.

Using several extraction methods including the QuEChERS approach, samples of both model and natural sediments were prepared. For the isolation of the target group of pesticides, two variants of two complementary extractions had to be used. Resulting extracts were analysed with LC/MS/MS.

Systematic method for the incorporation of the {(eta(6)-arene)Fe} fragment into carborane cages via [(eta(6)-arene)Fe]2+ dications. A series of [3-(eta(6)-arene)-closo-3,1,2-FeC2B9H11] complexes. Reliable synthesis of polymethylated [(eta(6)-arene)2Fe]2+ cations.

Developed was a systematic method for the incorporation of the {(eta(6)-arene)Fe} fragment into a carborane cage. Reactions between [(eta(6)-arene)(2)Fe](PF(6))(2) salts and Tl(2)[nido-7,8-C(2)B(9)H(11)] in refluxing (CH(2))(2)Cl(2) generated a series of [3-(eta(6)-arene)-closo-3,1,2-FeC(2)B(9)H(11)] neutral complexes with variable types of polymethylated arene ligands in the structure. The structures of durene and hexamethylbenzene complexes were established by X-ray diffraction analyses.

Boron(8) substituted nitrilium and ammonium derivatives, versatile cobalt bis(1,2-dicarbollide) building blocks for synthetic purposes.

The reaction of the cobalt bis(dicarbollide)(1-)() ion in the presence of t-butylbromide, acting as a potent Lewis acid activator, leads to the clean substitution of by the N-atom of acetonitrile (or benzonitrile), thus resulting in the smooth formation of [(8-RCN)-1,2-C(2)B(9)H(10))(1',2'-C(2)B(9)H(11))-3,3'-Co(iii)](0) (R = CH(3) or C(6)H(5)) ( and ). These compounds can serve as versatile precursors for the generation of a variety of other synthetically useful functional groups. The nitrogen atom of the nitrile C[triple bond, length as m-dash]N- bond in and is prone to the facile addition of nucleophiles.