X and Q-band EMR study of ultrasmall ZnMnFeO spinel nanoparticles fabricated under nonhydrolytic conditions.

In this work, we are showing the results of the X- and Q-band electron magnetic resonance measurements of ultra-small ZnMnFeO nanoparticles ( 8 nm) with a very narrow size distribution. The chosen synthetic route allows for precise structural modifications with a broad concentration range ( = 0, 0.2, 0.

Poly(levodopa)-Functionalized Polysaccharide Hydrogel Enriched in FeO Particles for Multiple-Purpose Biomedical Applications.

In recent years, there has been a significant increase in interest in the use of curdlan, a naturally derived polymer, for medical applications. However, it is relatively inactive, and additives increasing its biomedical potential are required; for example, antibacterial compounds, magnetic particles, or hemostatic agents. The stability of such complex constructs may be increased by additional functional networks, for instance, polycatecholamines.

Temperature effects induced by NIR photo-stimulation within I and II optical biological windows of seed-mediated multi-shell nanoferrites.

Different types of ferrite core-shell structures, namely CoFeO@CoFeO, CoFeO@FeO, CoFeO@MnFeO, and CoFeO@MnFeO@ZnFeO, were prepared by the seed-mediated approach. We show that this synthetic methodology offers great and important flexibility in the engineering of multi-shell ferrite nanoparticles which can be further used in various advanced applications. This impressive tool can be used for particle size tuning of homo- and heterostructures through convenient control of the concentration of metal acetylacetonates without the necessity of changing synthetic parameters, , temperature, time, and solvent.

Alternating magnetic field and NIR energy conversion on magneto-plasmonic FeO@APTES-Ag heterostructures with SERS detection capability and antimicrobial activity.

Multipurpose FeO@APTES-Ag heterostructures for mutual heat generation, SERS probing, and antimicrobial activity were fabricated using a three-step process. Silver metallic particles were precipitated on a thin silica shell that served as an interlayer with FeO nanocubes. The structural properties were studied by means of the powder X-ray diffraction technique, and selected area electron diffraction.

Synergic Temperature Effect of Star-like Monodisperse Iron Oxide Nanoparticles and Their Related Responses in Normal and Cancer Cells.

Magnetic nanoparticle (MNP) anisotropy has been tailored by the preparation of MNPs having different shapes (star-like, cubic, and polyhedral) using a self-modified rapid hot-injection process. The surface modification of MNPs was performed through etidronic ligand grafting with a strong binding affinity to mixed metal oxides, ensuring sufficient colloidal stability, surface protection, and minimized aggregation and interparticle interactions. The heating effect was induced by contactless external stimulation through the action of an alternating magnetic field and NIR laser radiation (808 nm).

Impact of Polyrhodanine Manganese Ferrite Binary Nanohybrids (PRHD@MnFeO) on Osteoblasts and Osteoclasts Activities-A Key Factor in Osteoporosis Treatment.

Osteoporosis is characterized by the reduction of bone mineral density and the weakness of the bone strength leading to fractures. Searching for new compounds that stimulate bone activity and their ability to reconstruct seems to be a promising tool in osteoporosis treatment. Here, we performed analyses comparing the impact of polyrhodanine (PRHD) and its derivatives on the viability (anti-proliferative tests), morphology and mitochondrial network (confocal microscopy) towards pre-osteoblasts (MC3T3-E1 cell line) and osteoclasts (4B12 cell line).

Rapid hot-injection as a tool for control of magnetic nanoparticle size and morphology.

The rapid hot-injection (HI) technique was employed to synthesize magnetic nanoparticles with well-defined morphology (octahedrons, cubes, and star-like). It was shown that the proposed synthetic approach could be an alternative for the heat-up and flow hot-injection routes. Instant injection of the precursor to the hot reaction mixture (solvent(s) and additives) at high temperatures promotes fast nucleation and particle directional growth towards specific morphologies.

CoMnFeO@PMMA Nanoparticles Promotes Preosteoblast Differentiation through Activation of Axis and Modulates Osteoclastogenesis under Magnetic Field Conditions.

The prevalence of osteoporosis in recent years is rapidly increasing. For this reason, there is an urgent need to develop bone substitutes and composites able to enhance the regeneration of damaged tissues which meet the patients' needs. In the case of osteoporosis, personalized, tailored materials should enhance the impaired healing process and restore the balance between osteoblast and osteoclast activity.

Multimodal polymer encapsulated CdSe/FeO nanoplatform with improved biocompatibility for two-photon and temperature stimulated bioapplications.

Multimodal polymer encapsulated CdSe/FeO nanoplatforms with dual optical and magnetic properties have been fabricated. We demonstrate that CdSe/FeO nanocapsules (NCs) upon excitation with UV radiation or NIR fs-laser excitation exhibit intense one- or two-photon emission at 535 nm, whereas the combination of an alternating magnetic field and 808 nm IR laser excitation results in heat generation. Since anticancer therapies require relatively high doses of FeO nanoparticles (NPs) to induce biologically relevant temperature jumps, the therapeutic effects of 0.

IGF-1 as selected growth factor multi-response to antidepressant-like substances activity in C57BL/6J mouse testis model.

Insulin-like growth factor (IGF-1) affects almost all cells in the body. Extremely important functions of this growth factor have been demonstrated in the brain and the reproductive system of both, females and males. Also, it is considered as a pro-inflammatory cytokine adjusting tissue homeostasis.

Multifunctional Properties of Binary Polyrhodanine Manganese Ferrite Nanohybrids-From the Energy Converters to Biological Activity.

The PRHD@MnFeO binary hybrids have shown a potential for applications in the biomedical field. The polymer cover/shell provides sufficient surface protection of magnetic nanoparticles against adverse effects on the biological systems, e.g.

Efficient non-contact heat generation on flexible, ternary hydroxyapatite/curdlan/nanomagnetite hybrids for temperature controlled processes.

The ternary HAp/curdlan/nanomagnetite hybrids with ceramic and polymer phase incorporation of magnetite nanoparticles (MNPs) were fabricated to study their heating ability under action of the alternating magnetic field (AMF), 808 nm near infrared laser radiation (NIR) and their synergic stimulation. The energy conversion was evaluated in terms of the specific absorption rate (SAR) as a function of the MNPs concentration in composites and to estimate their potential in temperature-controlled regenerative processes and hyperthermia. Measurements were carried out on dry and Ringer's solution soaked composite materials in order to mimic in situ conditions.

Correction: Efficient NIR energy conversion of plasmonic silver nanostructures fabricated with the laser-assisted synthetic approach for endodontic applications.

[This corrects the article DOI: 10.1039/D0RA06614A.].

Efficient NIR energy conversion of plasmonic silver nanostructures fabricated with the laser-assisted synthetic approach for endodontic applications.

Silver nanoparticles were synthesized with the laser-assisted wet chemical approach at room temperature. The effect of light exposure on the silver nanoparticles' spatial parameters shaping the localized surface plasmon resonance has been evaluated. The optical, structural and morphological characterizations of the Ag nanostructures were conducted with UV-VIS-NIR spectrophotometry, DLS and TEM techniques.

Yttrium-Doped Iron Oxide Nanoparticles for Magnetic Hyperthermia Applications.

Magnetic nanoparticles of FeO doped by different amounts of Y (0, 0.1, 1, and 10%) ions were designed to obtain maximum heating efficiency in magnetic hyperthermia for cancer treatment. Single-phase formation was evident by X-ray diffraction measurements.

Energy Conversion and Biocompatibility of Surface Functionalized Magnetite Nanoparticles with Phosphonic Moieties.

Magnetite nanoparticles (MNPs) were synthesized using two distinctly different approaches, co-precipitation (CP) and thermal decomposition (TD), and further surface functionalized with organophosphonic ligands containing different numbers of phosphonic groups. We have shown that it is possible to fabricate flower-like assemblies of MNPs through TD at lower temperatures, whereas CP MNPs formed agglomerates of particles with broad size distribution and irregular shapes. The effect of the organophosphonic ligands on the heating efficiency of the TD and CP MNPs under dual mode stimulation (simultaneous action of AMF and NIR laser radiation) was studied for the first time.

AMPK-mediated senolytic and senostatic activity of quercetin surface functionalized FeO nanoparticles during oxidant-induced senescence in human fibroblasts.

Cellular senescence may contribute to aging and age-related diseases and senolytic drugs that selectively kill senescent cells may delay aging and promote healthspan. More recently, several categories of senolytics have been established, namely HSP90 inhibitors, Bcl-2 family inhibitors and natural compounds such as quercetin and fisetin. However, senolytic and senostatic potential of nanoparticles and surface-modified nanoparticles has never been addressed.

Vascular endothelial growth factor (VEGF-A) and fibroblast growth factor (FGF-2) as potential regulators of seasonal reproductive processes in male European bison (Bison bonasus, Linnaeus 1758).

Growth factors: vascular endothelial growth factor A (VEGF-A) and fibroblast growth factor (FGF-2) were reported to affect normal physiological reproductive processes in human, domestic and free living animals. Moreover, some reports suggest that VEGF-A and FGF-2 may be directly involved in the control of the annual reproductive cycle of seasonally breeding animals but detailed knowledge is still missing. Our study aimed to demonstrate the expression of mRNA and protein for both factors in the tissues of testis and epididymis (caput, corpus, cauda) at different periods of the year (March, June, November, December) in European bison as a model of seasonally breeding animal.