Publications by authors named "Magdalena Kukla"
The genetics of eye colour has been extensively studied over the past few years, and the identified polymorphisms have been applied with marked success in the field of Forensic DNA Phenotyping. A picture that arises from evaluation of the currently available eye colour prediction markers shows that only the analysis of HERC2-OCA2 complex has similar effectiveness in different populations, while the predictive potential of other loci may vary significantly. Moreover, the role of gender in the explanation of human eye colour variation should not be neglected in some populations.
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- - The study investigates MCPIP1, a protein linked to cell differentiation and tumor suppression, which is minimally understood in the context of cancer, specifically neuroblastoma, a common childhood cancer.
- - Findings show that MCPIP1 is not expressed in primary neuroblastoma and enforcing its expression in neuroblastoma cells significantly reduces their growth and survival.
- - The research reveals that overexpressed MCPIP1 decreases levels of the choline transporter (CTL1) and identifies microRNA-3613-3p as a key player, suggesting that MCPIP1 may regulate this microRNA, impacting choline transport in cancer cells.