Publications by authors named "Magdalena Grabbe"
Front Vet Sci
August 2023
Article Synopsis
- Cryptosporidiosis, caused by an apicomplexan parasite, is a major diarrheal pathogen in calves and contributes to significant economic losses and health issues in both livestock and children.
- Neonatal bovine polymorphonuclear neutrophils (PMN) can form neutrophil extracellular traps (NETs) to combat this parasite, demonstrating their role in the innate immune response.
- This study reveals that neonatal bovine PMN's NETosis is triggered by the parasite and is dependent on the P2X1 receptor, suggesting its potential as a mechanism for controlling cryptosporidiosis.
