Is global DNA methylation in sporadic uterine adenocarcinomas in women a result of histological and clinical tumor advancement?

Aim: To find out the relationship, if any between the extent of the overall genomic DNA methylation, and clinical and pathological features of the sporadic endometrial adenocarcinomas in women.

Material: Genomic DNA was isolated from 44 primary uterine cancer tissue specimens. There were eight G1, 24 G2 and twelve G3 tumors.