[Cytometric assessment of apoptosis and aneuploidy in relation to survival time in osteosarcomas of children and adolescents].

Apoptosis programmed cell death takes place in response to many different stimuli, which include DNA damage. This is interest for therapeutic and prognostic purposes in neoplasms. Laboratory studies have shown that many anti-cancer agents (including cytostatics) achieve their cytotoxic effect by inducing apoptosis.