Emotional, inflammatory, and genetic factors of resilience and vulnerability to depression in patients with premenopausal breast cancer: A longitudinal study protocol.

Background: Psychosocial stress and depressive disorder have been associated with cancer as putative contributors to worse prognosis. On the other hand, cancer diagnosis is a recognised life event that can contribute to distress and depressive states. Humoral and cellular inflammation can promote depressive disorder by means of decreased monoamine synthesis, glutamate neurotoxicity, neurogenesis and neuroplasticity, dysregulated hypothalamic-pituitary-adrenal axis, and glucocorticoid resistance.

Post-acute COVID and long-COVID among adults and older adults in the State of Paraná, Brazil: protocol for an ambispective cohort study.

Introduction: Since 2020, the world has been going through a viral pandemic with a high morbidity and mortality rate along with the potential to evolve from an acute infection to post-acute and long-COVID, which is still in the process of elucidation. Diagnostic and prognostic research is essential to understand the complexity of factors and contexts involving the illness's process. This protocol introduces a study strategy to analyse predictors, sequelae, and repercussions of COVID-19 in adults and older adults with different disease severities in the State of Paraná, Brazil.

Perceived quality of life and associated factors in long COVID syndrome among older Brazilians: A cross-sectional study.

Aims And Objectives: This paper aims to: (a) determine the personal, sociodemographic, clinical, behavioural, and social characteristics of older Brazilians with clinical evidence of long COVID; (b) evaluate perceived quality of life and determine its association with personal, sociodemographic, behavioural, clinical and social variables; and (c) assess significant predictors of high perceived QoL.

Background: Given the inherent vulnerabilities of the ageing process, the older people are an at-risk group for both contagion of SARS-CoV-2 and the perpetuation of residual symptoms after infection, the so-called long COVID or post-COVID syndrome.

Design: A cross-sectional survey design using the STROBE checklist.

Factors associated with risk related to the use of psychoactive substances by men deprived of their liberty.

Objective: to evaluate the factors associated with risk related to the use of psychoactive substances in male inmates of a prison in a city in the South of Brazil.

Method: a cross-sectional data from 220 men deprived of liberty, inmates of a provisional custody institution in the State of Paraná, collected with a screening instrument and questionnaire. Binary logistic regression and odds ratio analysis were used to verify associations between risk related to substance use and socio-demographic characteristics of living conditions before incarceration and current incarceration.

Prevalence of non-communicable chronic diseases and associated factors in deaf people.

Objective: To analyze the prevalence and factors associated with non-communicable chronic diseases in deaf people.

Methods: Cross-sectional study with 110 deaf people in Maringá-Paraná, selected using the snowball sampling technique. Data were collected from February to August 2019, using a structured instrument; and, in the analysis, multiple logistic regression was used.

Spatial correlation of covid-19 with intensive care unit beds in Paraná.

Objective: To analyze the spatial correlation between confirmed cases of covid-19 and the intensive care unit beds exclusive to the disease in municipalities of Paraná.

Methods: This is an epidemiological study of ecological type which used data from the Epidemiological Report provided by the Department of Health of Paraná on the confirmed cases of covid-19 from March 12, 2020, to January 18, 2021. The number of intensive care beds exclusive to covid-19 in each municipality of Paraná was obtained by the Cadastro Nacional de Estabelecimentos de Saúde (CNES - National Registry of Health Establishments), provided online by the Departamento de Informática do Sistema Único de Saúde (Datasus - Informatics Department of the Brazilian Unified Health System).

Stress-Related Growth Scale-Short Form: A Portuguese validation for cancer patients.

Abstract Background/objective: Cancer can be extremely disruptive, triggering high levels of distress, and at the same time transformative, promoting perceptions of positive life changes and growth. This study aims to analyze the psychometric proprieties of the Stress-Related Growth Scale Short-Form (SRGS-SF) in cancer patients.

Method: 209 Cancer patients heterogeneous in disease stage and diagnosis completed: clinical and sociodemographic information, Distress Thermometer, Positive and Negative Affect Schedule, Visual-analogue Scale of Perceived Positive Life Changes, and Stress-Related Growth Scale-Short Form.

Dialogic educational practices in the context of child intoxication: an approach based on Paulo Freire.

Objective: To analyze the knowledge and practices of education of Family Health Strategy professionals regarding child intoxication for the autonomy and empowering of the families.

Methods: Qualitative research, carried out through semistructured interviews with 50 professionals from the Family Health Strategy of a city in the Northwest of Paraná. Data was problematized using Paulo Freire's sociocultural approach and its concepts of dialogism and autonomy.

Elemental plasma content and urinary excretion in vineyard farmers occupationally exposed to pesticides in southern Brazil.

This is a cross-sectional study with data and biological material collection from vineyard farmers in southern Brazil. An interview was carried out through a questionnaire developed according to the reference guide of the state government. Plasma and urine samples were screened for Aluminum, Chromium, Manganese, Copper, Nickel, Cobalt, Zinc, Arsenic, Selenium, Cadmium, Antimony, Barium, Mercury, Lead and Uranium, with a technique for fast determination of these elemental contents in biological material utilizing dynamic reaction cell inductively coupled mass spectrometry.

Active teaching strategies improve nursing knowledge and skills to assist burn victims.

Objective: to evaluate the impact of an educational intervention, on nurses' self-perception, about knowledge and skills for initial care for burn victims.

Methods: a quasi-experimental study of the type before and after, with 18 nurses who assist burn victims. The intervention was carried out for 11 days in face-to-face meetings and online activities, and comprised active case-based learning strategies, simulation training, concept maps and digital portfolio.

Experiences of family members of drivers who violate the law against rinking and driving and its repercussions.

Objectives: to understand the experiences of family members of drivers who violate the law against drinking and driving and the post-penal repercussions.

Methods: a qualitative study, with family members of drivers who violated the law against drinking and driving who participated in the Projeto Justiça e Sobriedade no Trânsito de Maringá - PR (Traffic Justice and Sobriety Project in Maringá - PR). Data collection was carried through semi-structured interviews, analyzed through thematic analysis.

Outcome measures for disease-modifying therapies in relapsing multiple sclerosis randomized clinical trials: a scoping review protocol.

Objective: The objective of the review is to explore randomized controlled trials on disease-modifying therapies for relapsing multiple sclerosis to identify and quantify the different outcome measures, instruments and definitions of efficacy, safety outcomes, health-related quality of life instruments and population subgroups.

Introduction: A wide range of therapies are available for relapsing multiple sclerosis, as well as a wide range of outcome measures and definitions, which can be explained by the absence of a core outcome set for this disease. Establishing a core outcome set is fundamental for guiding future studies as they improve the consistency and relevance of new findings and enable the results of trials to be compared and combined.

Efficacy outcomes reported in trials of multiple sclerosis: A systematic scoping review.

Background: This study aimed to map the outcome measures of clinical efficacy reported in Randomized Controlled Trials (RCT) to evaluate disease-modifying therapies (DMT) in patients with relapsing forms of multiple sclerosis (RMS).

Methods: A systematic scoping review was performed to identify RCT that assessed the efficacy of DMT in adult patients with RMS. Searches were conducted in PubMed, Scopus, and The Cochrane Controlled Register of Trials and complemented by manual search.

Homeless population: characterization and contextualization by census research.

Objectives: to analyze characteristics of homeless people and factors associated with living on the streets.

Methods: a census-type sectional survey carried out between 2015 and 2018, in the municipality of Maringá-Paraná. A total of 701 homeless answered a structured questionnaire with sociodemographic data, living conditions, and drug use.

Drug use by men admitted to a psychiatric hospital.

Objective: to assess risk related to drug use in men admitted to a psychiatric hospital and to identify associations with sociodemographic, socioeconomic variables, and risk conditions.

Method: a cross-sectional study with the application of a screening test in 209 participants hospitalized for mental and behavioral disorders due to the use of psychoactive substances. Statistical analysis was performed using descriptive statistics and adjustment of a binary logistic regression model for moderate or high risk of drug use.

Meanings and dimensions of cancer by sick people - a structural analysis of social representations.

Objective: To describe the contents and structure of the social representation of cancer.

Method: A qualitative study based on the Theory of Social Representations, carried out in a High Complexity Care Unit in Oncology. Data collection included a socio-occupational and clinical characterization questionnaire and free evocations form from 100 cancer patients in chemotherapy treatment and in-depth interviews with 29 of them.

Men's perceptions on educational intervention participation at workplace.

Objective: todescribe the application of educational intervention performed with working men and identify, according to their perceptions, the main results obtained.

Methods: a descriptive and exploratory research, of qualitative nature, developed in a municipality of Southern Brazil, with 35 metallurgists. Data were collected between March and June 2014, through the recording of the operating groups and participant observation.

Feelings of families regarding drug dependence: in the light of comprehensive sociology.

Objective: to understand the feelings of families before drug dependence.

Method: exploratory, analytical and qualitative study carried out with families of drug users, which are followed up by the Centro de Atenção Psicossocial Álcool e Drogas (Psychosocial Care Center for Alcohol and DARUGS). The collection of data took place by in-depth interview, with the support of field diary.

[Stress symptoms in female nurses working in emergency rooms].

This is a sectional study carried out in an emergency room, with the purpose of identifying the association of socio-demographic, occupational and economic data in nursing workers presenting stress symptoms. Data was collected from 33 subjects, in July and August 2009, using an inventory of stress symptoms for adults. Results show that most of the workers presented stress symptoms at resistance and almost-exhaustion stages, with presence of psychological and physical symptoms.

Family ties of crack cocaine users cared for in a psychiatric emergency department.

This study characterizes the family ties of crack cocaine users cared for in a psychiatric emergency department in southern Brazil. It is a qualitative study with a series of cases carried out in the city of Maringá, PR, Brazil from April to June 2010. Data were collected through semi-structured interviews, analyzed using content analysis, and organized into two categories: family ties as facilitators in the use of crack cocaine and other drugs; and fragmented family ties of crack users.

Monitorization of drug content in furosemide and lorazepam tablets stored in multidose pill boxes.

Background: Therapeutic nonadherence is a major health problem, particularly when therapeutic regimens are complex and long-lasting. Therefore, tools such as multidose pill boxes have been designed to provide the means for higher therapeutic compliance. However, no studies are available reporting on their capacity to keep the drug content of the stored tablets unaltered.

[The role of family relationships in the initiation of street drug abuse by institutionalized youths].

The objective of this study was to analyze the role of family relationships in the initiation of streetdrug abuse by youths, meeting social-educational measures, considering the severity of the problems that drug abuse brought to the youths and their families. This descriptive, cross-sectional study used a case series design and was developed in the cities of Rolândia and Cambé (Brazil), at the Vida Nova Halfway House, with institutionalized youths and their parents or responsible adults in March 2007. Data was collected from institutional records and the instruments used were two interview forms.

Knowledge about AIDS and drugs among undergraduate students in a higher education institution in the state of Paraná.

The main objective of this study was to measure the knowledge of undergraduate nursing students about Acquired Immunodeficiency Syndrome (AIDS) and drugs. The study was carried out in 2007 with a random sample of 289 undergraduate students at a State University in the Northwest of Paraná, Brazil. The students self-applied a questionnaire validated by experts.

[Learning about the social support provided to the family caregiver assisting a family dependent].

The elderly suffering disability caused by diseases need a network of support in order to continue feeling socially active. This study aims at characterizing the social support provided to the family caregiver who looks after an elderly dependent, in Brazil. A descriptive study with qualitative approach was conducted at the municipality of Jandaia do Sul, Paraná, Brazil.