Systemic redox modifications in senile cataract.

Unlabelled: Recent studies on cataract formation focus on a primary role of systemic oxidative stress, generated outside the lens. Plasma inflammatory markers are associated with senile cataract.

Objective: The aim of this study was to find correlations between blood oxidative stress markers and some inflammatory plasma markers in cataractous patients.

Oxidative stress parameters in hemodialysis patients with or without diabetes.

Oxidative stress (imbalance of antioxidant and prooxidants in favour of the later) is considered to be a feature of diabetes and chronic renal failure. Carbonyl stress defined as accumulation of reactive carbonyl compounds due to excess production or disturbed clearance from the body is thought to amplify oxidative stress in these conditions. The accumulation of carbonyl compounds can be also a consequence of oxidative stress.

Plasma redox status and premature onset of senile cataract.

Unlabelled: Dysfunction of the lens due to opacification is called cataract. Senile cataract is associated with old age. It is estimated that the need for cataract extractions would be diminished by half if onset of cataract would be delayed by only ten years.

Influence of epoietinum therapy on the oxidative stress in haemodialysis patients.

Background: The causes of oxidative stress in haemodialysis (HD) patients are still controversial. Beside the uraemic state and dialysis-related factors, adjuvant drug therapies such as epoietinum (rHuEpo) and intravenous iron were involved.

Methods: Several parameters related to oxidative stress were assessed by spectrophotometry in stable HD patients, treated for at least 2 months with epoietinum (n = 14; mean dose = 97.