Urinary cortisol-creatinine ratio in dogs with hypoadrenocorticism.

Background: Basal serum cortisol (BSC) ≥2 μg/dL (>55 nmol/L) has high sensitivity but low specificity for hypoadrenocorticism (HA).

Objective: To determine whether the urinary corticoid:creatinine ratio (UCCR) can be used to differentiate dogs with HA from healthy dogs and those with diseases mimicking HA (DMHA).

Animals: Nineteen healthy dogs, 18 dogs with DMHA, and 10 dogs with HA.

Development and assessment of a novel precordial lead system for accurate detection of right atrial and ventricular depolarization in dogs with various thoracic conformations.

Objective: To assess recording accuracy of right atrial and ventricular depolarization during 12-lead ECG when precordial lead V was positioned at each of 5 locations on the thorax of dogs with various thoracic conformations.

Animals: 60 healthy client-owned dogs.

Procedures: 20 dogs were allocated to each of 3 groups (brachymorphic, mesomorphic, or dolichomorphic) on the basis of thoracic conformation.

Case-control study of plasma mean platelet component concentration and survival analysis for dogs with immune-mediated hemolytic anemia.

OBJECTIVE To determine whether dogs with immune-mediated hemolytic anemia (IMHA) had a low plasma mean platelet component (MPC) concentration and whether MPC was associated with outcome. DESIGN Retrospective case-control study and survival analysis. ANIMALS 95 dogs with IMHA (cases) as well as 95 healthy dogs and 95 sick dogs without IMHA (controls) matched to cases by age, reproductive status, and breed.

Determining optimal therapy of dogs with chronic enteropathy by measurement of serum citrulline.

Background: Serum concentration of citrulline is a useful biomarker in human intestinal disease and indicates globally reduced enterocyte mass and absorptive function in various disease states.

Objectives: To determine whether serum citrulline concentration is a biomarker in chronic enteropathy (CE) in dogs, to provide useful information regarding optimal treatment or to predict outcome.

Animals: Seventy-four dogs with CE and 83 breed- and age-matched hospital controls with no clinical signs of intestinal disease.

Agarose gel serum protein electrophoresis in cats with and without lymphoma and preliminary results of tandem mass fingerprinting analysis.

Background: Serum electrophoretic profiles in cats are poorly characterized with respect to the proteins that comprise the globulin fractions, and interpretation of the electrophoretograms is routinely done in the absence of information about identity of the proteins found within each fraction.

Objectives: The aims of this study were to compare protein fractions separated by serum protein electrophoresis (SPE) in healthy cats and in cats with lymphoma and to confirm some component proteins in the major fractions following SPE using tandem mass fingerprinting analysis (TMFA).

Methods: Total protein concentration was measured and agarose gel SPE performed on serum from 14 healthy cats and 14 cats with lymphoma.