How studies on zoonotic risks in wildlife implement the one health approach - A systematic review.

Background: The recent COVID-19 pandemic and the emergence of infectious diseases at the human-animal interface highlight the global challenge of mitigating zoonotic risks. The One Health approach emphasizes the interconnectedness of human, animal, and environmental health, urging for holistic and interdisciplinary strategies in disease prevention. Despite growing interest, the attention to wildlife in pandemic prevention remains limited.

Unveiling the Enigmatic nature of six neglected Amazonian Leishmania (Viannia) species using the hamster model: Virulence, Histopathology and prospection of LRV1.

American tegumentary leishmaniasis (ATL) is highly endemic in the Amazon basin and occurs in all South American countries, except Chile and Uruguay. Most Brazilian ATL cases are due to Leishmania (Viannia) braziliensis, however other neglected Amazonian species are being increasingly reported. They belong to the subgenus L.

Spatial and Temporal Distribution of and Oviposition on the Coast of Paraná, Brazil, a Recent Area of Dengue Virus Transmission.

and are considered the most important vectors of arboviruses in the world. is the primary vector of dengue, urban yellow fever, chikungunya and zika in Brazil, and is considered a potential vector. Distribution patterns and the influence of climatic variables on the oviposition of and were evaluated in Morretes, a tourist city in the coastal area of Paraná State, Brazil, which has recently been experiencing cases of dengue fever.

Predictive modeling of sand fly distribution incriminated in the transmission of Leishmania (Viannia) braziliensis and the incidence of Cutaneous Leishmaniasis in the state of Paraná, Brazil.

Southern Brazil concentrates a considerable number of cases of cutaneous leishmaniasis reported since 1980, and Paraná is the state that most records CL cases in the region. The main sand fly species incriminated as vectors of Leishmania (Viannia) braziliensis (Vianna,1911) are Migonemyia (Migonemyia) migonei (França, 1920), Nyssomyia (Nyssomyia) neivai (Pinto, 1926) and Nyssomyia (Nyssomyia) whitmani (Antunes & Coutinho, 1936). In this study, we evaluated areas with climatic suitability for the distribution of these vectors and correlated these data with CL incidence in the state.

Cutaneous leishmaniosis in naturally infected dogs in Paraná, Brazil, and the epidemiological implications of Leishmania (Viannia) braziliensis detection in internal organs and intact skin.

Environmental changes have occurred over the years, altering the eco-epidemiological pattern of leishmaniosis in the State of Paraná, Brazil, involving the pillars of the cycle (parasite, vectors, reservoir, and environment) and their interaction. Much has been discussed about the dog's role as a reservoir of the Leishmania (Viannia) braziliensis Vianna, 1911 transmission cycle. However, this question remains unanswered.

Can equids be a reservoir of Leishmania braziliensis in endemic areas?

In this study, we detected Leishmania (Viannia) braziliensis infection in equids living in endemic regions of cutaneous leishmaniasis. To determine the role of these animals in the Leishmania cycle, we used two approaches: serological and molecular methods. Antibodies to the parasite were assayed using the Enzyme Linked Immunosorbent Assay (ELISA).

Detection of Neospora caninum DNA in capybaras and phylogenetic analysis.

The role of rodents in the sylvatic cycle of Neospora sp. and in the neosporosis epidemiology is still uncertain. The aim of the present work was to detect Neospora caninum and to determine its prevalence in capybaras (Hydrochaeris hydrochaeris), to help elucidate the role of this rodent in the life cycle of the parasite.

Spinocerebellar ataxias: microsatellite and allele frequency in unaffected and affected individuals.

The diagnosis and incidence of spinocerebelar ataxias (SCA) is sometimes difficult to analyze due the overlap of phenotypes subtypes and are disorders of mutations caused by CAG trinucleotide repeat expansion. To investigate the incidence of the SCA in Southern Brazil, we analyzed the trinucleotide repeats (CAG)n at the SCA1, SCA2, SCA3, SCA6 and SCA7 loci to identify allele size ranges and frequencies. We examined blood sample from 154 asymptomatic blood donors and 115 individuals with progressive ataxias.

Low gene flow of Aedes aegypti between dengue-endemic and dengue-free areas in southeastern and southern Brazil.

We present a population genetic study of Aedes aegypti in Brazil using isoenzyme markers. Four polymorphic loci were used to examine 11 mosquito collections at four periods in 2003. Samples from a dengue-endemic area (southeastern region) and a dengue-free area (southern region) connected by an important network of roads and railways were analyzed.

Higher genetic variation estimated by microsatellites compared to isoenzyme markers in Aedes aegypti from Rio de Janeiro.

Aedes aegypti populations from five districts in Rio de Janeiro were analyzed using five microsatellites and six isoenzyme markers, to assess the amount of variation and patterns of gene flow at local levels. Microsatellite loci were polymorphic enough to detect genetic differentiation of populations collected at small geographic scales (e.g.