A prospective, observational study of fidaxomicin use for infection in France.

Objective: To describe the characteristics, management and outcomes of hospitalised patients with infection (CDI) treated with and without fidaxomicin.

Methods: This prospective, multicentre, observational study (DAFNE) enrolled hospitalised patients with CDI, including 294 patients treated with fidaxomicin (outcomes recorded over a 3-month period) and 150 patients treated with other CDI therapies during three 1-month periods. The primary endpoint was baseline and CDI characteristics of fidaxomicin-treated patients.