Publications by authors named "Magali Aparecida Rodrigues"
A prion-derived copper(II)-binding peptide was assembled onto a gold electrode for the building of a voltammetric biosensor for measuring the Cu metal ion in biological samples. The chosen sequence was H-CVNITKQHTVTTTT-NH, with an appended cysteine residue for binding to the gold surface as a self-assembled monolayer and a histidine residue as the anchorage point for copper(II) complexation. The biosensor showed a linear range of 10 to 10 M with an 8.
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- - The sugarcane giant borer is a major pest that leads to significant losses in sugarcane crops, and traditional control methods like chemicals and manual efforts are largely ineffective.
- - In this study, researchers evaluated the toxicity of four Cry toxins (Cry1A and Cry2Aa) on the borer's larvae, finding that Cry1Ac was the most effective, showing significantly higher activity compared to the other toxins.
- - Molecular analysis identified potential interactions between Cry1Ac and specific receptors, suggesting that particular amino acids enhance the toxin's effectiveness, which could inform the development of genetically modified sugarcane resistant to this pest.
In a large variety of organisms, antimicrobial peptides (AMPs) are primary defenses against pathogens. BP100 (KKLFKKILKYL-NH), a short, synthetic, cationic AMP, is active against bacteria and displays low toxicity towards eukaryotic cells. BP100 acquires a α-helical conformation upon interaction with membranes and increases membrane permeability.
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