Publications by authors named "Maeve Elizabeth Byrne"
Front Immunol
August 2024
Article Synopsis
- Large-scale production of functional natural killer (NK) and CAR-NK cells is currently a major challenge in NK-based cancer immunotherapy.
- A new method using G-Rex 100M bioreactors was developed, which enhances oxygen delivery and allows for the effective expansion of these cells in larger volumes for therapy.
- The NK and CAR-NK cells produced using this method maintained their ability to target and kill cancer cells and showed good viability after freezing, indicating potential for future clinical use as accessible "off-the-shelf" therapies.
