Publications by authors named "Maedeh Najafizadeh"

Article Synopsis
  • - The study investigates the clinical symptoms and physical findings in patients infected with COVID-19, comparing hypertensive (high blood pressure) and nonhypertensive groups through a single-center retrospective observational analysis of 280 patients.
  • - Among the participants, the average age was about 67.75 years, with a notable 17% in-hospital mortality rate, and no significant differences were found in common symptoms like fever and cough between the two groups.
  • - The results indicate that hypertension is linked to worse outcomes and higher mortality in COVID-19 patients, emphasizing the need for proper blood pressure management and care for older patients with hypertension and other conditions.
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Infective endocarditis (IE) rarely presents with cutaneous manifestations due to earlier diagnosis and treatment. We present a case of middle-aged male patient presenting with an erythematous papular rash in the upper extremities and left knee, further progressing into painful ulcers with crusted and necrotic center in the arms and fingers. These cutaneous lesions were further followed by shaking chills and fever, which brought the patient to our hospital.

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Objective: Immune changes play fundamental roles in the pathogenesis and severity of coronavirus disease 2019 (COVID-19). Previous studies have revealed alterations in immune responses of patients with non-severe and severe COVID-19. Therefore, this study investigated whether interleukin-27 (IL-27) and interleukin-32 (IL-32) levels may be considered as predicting factors for determining the severity and outcome of COVID-19.

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