Publications by authors named "Mae-Lynn C Bastion"

Objectives: Topical insulin (TI) at 25 IU/mL effectively normalizes healing of corneal epithelium and dry eye in diabetic patients. We aim to determine physicochemical stability and sterility of TI in sodium hyaluronate 0.18% (TI-artificial tears [AT]) in an eye drop formulation.

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Background: Fireworks are known to cause severe ocular injuries. This study was intended to examine the pattern and visual outcomes of firework-related severe eye injuries in Malaysia.  Methods: A retrospective review of fireworks-related eye injuries was conducted in Malaysia from 1 July 2022 to 30 June 2023.

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Significance: Acute macular neuroretinopathy (AMN) is a rare disease that causes transient or permanent visual disturbance. The exact etiology remains unknown, but vascular compromise of the deep retinal capillary plexus was postulated as the main mechanism. Retinal vascular event post-coronavirus disease 2019 (COVID-19) infection is recently highlighted during the pandemic, which includes AMN.

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Article Synopsis
  • The paper looks at how inherited retinal diseases (IRD) are diagnosed and treated in the Asia-Pacific region.
  • They surveyed 36 centers about their practices, including how they collect patient information and provide help for low vision.
  • The results showed there are important gaps, like many centers not having a database for patients, not enough genetic counselors, and a need for better support for low-vision rehabilitation.
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  • Retinal detachment from eye trauma (TrRD) is a major cause of blindness and visual impairment globally, with diagnosis dependent on trauma history.
  • The conditions leading to TrRD include various incidents such as workplace injuries, sports accidents, and road traffic collisions.
  • There is a lack of detailed discussion in existing literature on the underlying causes, treatment, and results of TrRD, prompting a thorough review of these aspects in the current study.
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Background: Eye removal surgeries, also called anophthalmic surgeries, are usually performed for a painful blinded eye due to various underlying causes. In this case review, we intended to study the indications, the types of anophthalmic surgeries, and post-operative complications related to eye removal surgeries.

Method:  Five years of retrospective case review of surgical eye removals was conducted from 1st June 2018 to 31st May 2023 at Hospital Canselor Tuanku Muhriz (HCTM), University of Kebangsaan Malaysia (UKM).

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Rhegmatogenous retinal detachment (RRD) is an ocular emergency as it is sight-threatening and requires urgent surgical intervention. Ulcerative colitis (UC) is an immune-mediated inflammatory bowel disease that can present with ocular manifestations. The objective of this case report is to share the rare presentation of RRD associated with UC leading to diagnosis and management dilemmas.

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A 61-year-old Malaysian Chinese man who has high myopia complained of both eye floaters. Spectral-domain optical coherence tomography (SD-OCT) of the macula showed bilateral posterior staphyloma with right eye (RE) foveoschisis without macula detachment, which had been stable for a seven-year follow-up. When bilateral YAG laser vitreolysis could not alleviate his symptoms, he underwent pars plana vitrectomy with the inducement of posterior vitreous detachment, first in the left eye, followed by the RE one month later.

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A 12-year-old boy with underlying severeand poorly controlled atopic dermatitis (AD) associated with atopic conjunctivitis and rhinitis presented with a right painless blurring of vision for two weeks. On examination, his right eye visual acuity was 1/60,with grade 1 relative afferent pupillary defect (RAPD). Anterior segment examination revealed anterior uveitis with dense posterior subcapsular cataract and hazy fundus view.

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Article Synopsis
  • The Asia-Pacific region, housing about 60% of the world's population, lacks extensive knowledge about hereditary eye diseases, necessitating a regional collaboration to enhance precision medicine for affected patients.
  • The Asia-Pacific Inherited Eye Disease (APIED) network, consisting of 55 members from 35 centers across 12 countries, aims to address these gaps in understanding inherited retinal diseases (IRDs) by bringing together experts in the field.
  • The network's goals include improving genetic diagnosis of IRDs, standardizing phenotyping practices, and creating high-quality patient registries to support care and research in both regional and international contexts.*
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Background: Diabetic keratopathy (DK) occurs in 46%-64% of patients with diabetes and requires serious attention. In patients with diabetes, the healing of corneal epithelial defects or ulcers takes longer than in patients without diabetes. Insulin is an effective factor in wound healing.

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Introduction: During the COVID-19 pandemic, non-frontline medical disciplines, including ophthalmology, were advised to minimize their services to channel crucial healthcare resources to manage the surge in COVID-19 cases. The ophthalmology department postponed all non-urgent appointments and elective surgical procedures. However, little is known about the visual and mental health impact of these changes in ophthalmology services.

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Background: This study aimed to report a case of outer lamellar macular hole and outer retinal detachment within myopic foveoschisis (MF) post-cataract surgery.

Case Presentation: An elderly female patient with bilateral high myopia and pre-existing myopic foveoschisis underwent uncomplicated sequential cataract surgeries 2 weeks apart. She was able to achieve a satisfactory visual outcome for her left eye with stable myopic foveoschisis and visual acuity of 6/7.

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Purpose: To evaluate the corneal topographical changes in vernal keratoconjunctivitis (VKC) subjects using OCULUS Pentacam.

Design: This was a cross-sectional study.

Methods: VKC patients and normal subjects who fulfilled the inclusion and exclusion criteria were recruited by convenience sampling into the study.

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Oxidative stress is one of the common factors leading to age-related eye diseases in older adults. Factors such as high oxygen consumption, high concentration of polyunsaturated fatty acids, and cumulative exposure to high-energy visible light in the eyes, lead to excessive generation of reactive oxygen species, hence triggering apoptosis of ocular cells and giving rise to ophthalmic diseases. Dietary supplements such as carotenoids, anthocyanins, and vitamins have antioxidant properties which may be of benefit in retaining better vision or reversing vision impairment; thus, studies have been conducted to understand the role of dietary supplements in the treatment or prevention of ophthalmic diseases.

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Purpose: To determine the effectiveness of laser vitreolysis in terms of contrast sensitivity function (CSF) and vision-related quality of life (VRQol) for symptomatic floaters due to posterior vitreous detachment (PVD).

Materials: This is an interventional study that involved 57 eyes of 45 patients with symptomatic floaters for more than 3 months. Patients underwent one to three sessions of vitreolysis via Neodymiun-doped Yttrium Aluminum Garnet (Nd:YAG) laser.

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Non-contact condensing lenses (NCLL) are a requirement in ophthalmology examinations. To date, there have been no studies on the types of bacteria found on handheld lenses used to examine patients in an ophthalmology clinic. The BD BACTEC Peds Plus broth (BACTEC-PP) culture method can isolate more organisms as compared to conventional culture plates (CCP) from NCLL.

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Purpose: The aim of this study was to evaluate the choroidal and photoreceptor thickness in highly myopic eyes and its correlation with visual acuity.

Methods: This is a cross-sectional, observational study involving 57 eyes of 57 highly myopic subjects [spherical equivalent ≥ -6 diopters (D) or axial length ≥ 26 mm] seen in a tertiary institutional center. Eyes with any clinical evidence of maculopathy or amblyopia were excluded.

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Purpose: There are no effective treatments currently available for optic nerve transection injuries. Stem cell therapy represents a feasible future treatment option. This study investigated the therapeutic potential of human umbilical cord-derived mesenchymal stem cell (hUC-MSC) transplantation in rats with optic nerve injury.

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Craniopharyngioma is a rare and benign sellar and suprasellar region tumour. It rarely manifests during pregnancy. We report a 32-year-old primigravida at 19 weeks of gestation with a craniopharyngioma, presenting with visual disturbances during pregnancy.

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Article Synopsis
  • Tuberculous pleural effusion (TPE) is a challenging diagnosis due to its paucibacillary nature, often requiring a combination of clinical evaluation and imaging to confirm.
  • A 25-year-old male exhibited symptoms like cough, fever, and weight loss, and although he was initially misdiagnosed with azathioprine-induced lung injury, further testing indicated TPE.
  • Effective treatment with anti-tubercular therapy led to a complete recovery, highlighting the need for vigilance in diagnosing TPE, especially in immunocompromised patients in tuberculosis-endemic areas.
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The aim of this study is to report an unusual case of retinal racemose haemangioma (RRH) in a child resulting in optic neuropathy and its optical coherence tomography angiography (OCT-A) findings. This is a retrospective case report. For almost a year, a 13-year-old girl experienced gradual, painless, generalized blurred vision in her right eye.

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Article Synopsis
  • Diabetes mellitus (DM) is a growing global health issue, particularly affecting younger women, and can lead to serious eye conditions like diabetic retinopathy (DR), which can threaten vision if not managed properly.
  • Pregnancy poses additional risks for women with DR, as baseline conditions can lead to severe complications, with 10% of women with early-stage DR progressing to more severe forms during this time.
  • Effective management strategies include prepregnancy counseling, careful monitoring during pregnancy, and selecting appropriate treatments while considering potential risks to both the mother and fetus.
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Article Synopsis
  • The text mentions a correction to a previously published article.
  • The article in question has the DOI: 10.3389/fcell.2021.652017.
  • This indicates that there may have been errors or updates that need to be addressed for clarity or accuracy in the original research.
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A 75-year-old man with underlying left eye idiopathic orbital inflammatory disease and bilateral glaucoma suspect with cup disc ratio 0.7 underwent right eye phacoemulsification. Intraoperatively, Descemet tear and Descemet membrane detachment (DMD) occurred.

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