Publications by authors named "Mae Morton-Dutton"
Importance: Drug-resistant temporal lobe epilepsy (TLE) has been associated with hippocampal pathology. Most surgical treatment strategies, including resection and responsive neurostimulation (RNS), focus on this disease epicenter; however, imaging alterations distant from the hippocampus, as well as emerging data from responsive neurostimulation trials, suggest conceptualizing TLE as a network disorder.
Objective: To assess whether brain networks connected to areas of atrophy in the hippocampus align with the topography of distant neuroimaging alterations and RNS response.
Article Synopsis
- * The research compared brain lesions causing parkinsonism with those causing seizures using advanced brain network mapping techniques.
- * Findings indicate that lesions related to parkinsonism and seizures are associated with distinct, opposite brain networks, particularly highlighting the role of the substantia nigra in this relationship.
Article Synopsis
- Recent studies suggest a link between parkinsonism and seizures, but it's unclear which causes which.
- Researchers analyzed brain lesions in patients with parkinsonism and those with seizures to understand their connection to brain networks.
- They found that lesions associated with parkinsonism and seizures mapped to opposite brain networks, highlighting a distinct neuroanatomical relationship that clarifies previous conflicting findings.