Publications by authors named "Maduke Kula"
Article Synopsis
- International guidelines suggest stopping cervical screenings at age 50 if two consecutive tests are negative, but many women over 50 in LMICs, like Botswana, haven't had the chance to screen.
- The study analyzed data from two separate cohorts—one for screening with 2,570 women aged 30+ and another with 1,520 cervical cancer patients—to understand the prevalence of cervical dysplasia and cancer stages by age and HIV status.
- Results showed similar prevalence rates of cervical intraepithelial neoplasia (CIN) between women aged 30-49 and 50+, regardless of HIV status, indicating no significant differences in disease prevalence across these age groups.
Feasibility and acceptability of an HPV self-testing strategy: lessons from a research context to assess for ability to implement into primary care at a national level in Botswana.
Front Glob Womens Health
January 2024
Background: The WHO strategy for cervical cancer elimination strives to achieve 70% coverage with high-performance cervical screening. While few low- and middle-income countries have achieved this, high-risk human papillomavirus (hrHPV) self-testing creates the possibility to rapidly upscale access to high-performance cervical screening across resource settings. However, effective hrHPV screening requires linkage to follow-up, which has been variable in prior studies.
View Article and Find Full Text PDFObjective: Guidelines for effective triage following positive primary high-risk human papillomavirus (HPV) screening in low- and middle-income countries with high human immunodeficiency virus (HIV)-prevalence have not previously been established. In the present study, we evaluated the performance of three triage methods for positive HPV results in women living with HIV (WLHIV) and without HIV in Botswana.
Methods: We conducted baseline enrollment of a prospective cohort study from February 2021 to August 2022 in South-East District, Botswana.