Am J Physiol Renal Physiol
February 2017
Aquaporin 11 (AQP11) is a channel protein with unknown biological function that is expressed in multiple tissues, including the kidney proximal tubule (PT) epithelium. Constitutive deletion of in mice () results in early postnatal vacuolization in the PT and development of apparent cysts at 2 wk of age. Electron microscopy of adult mouse PT cells revealed a dilated rough endoplasmic reticulum.
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