Long-lived and Efficient Optomechanical Memory for Light.

We demonstrate a memory for light based on optomechanically induced transparency. We achieve a long storage time by leveraging the ultralow dissipation of a soft-clamped mechanical membrane resonator, which oscillates at MHz frequencies. At room temperature, we demonstrate a lifetime T_{1}≈23  ms and a retrieval efficiency η≈40% for classical coherent pulses.

Introducing quality clusters in general practice - a qualitative study of the experiences of cluster coordinators.

Background: In 2018, the concept of clusters was introduced as a new model for data-driven quality improvement in general practice in Denmark. However, there is little research on the development and implementation of general practice clusters. The study explores how the cluster coordinators responsible for leading the clusters forward enacted and experienced their role during the early years of the clusters with attention to the challenges and enablers perceived in the process.

Detection of oedema on optical coherence tomography images using deep learning model trained on noisy clinical data.

Purpose: To meet the demands imposed by the continuing growth of the Age-related macular degeneration (AMD) patient population, automation of follow-ups by detecting retinal oedema using deep learning might be a viable approach. However, preparing and labelling data for training is time consuming. In this study, we investigate the feasibility of training a convolutional neural network (CNN) to accurately detect retinal oedema on optical coherence tomography (OCT) images of AMD patients with labels derived directly from clinical treatment decisions, without extensive preprocessing or relabelling.

Explainable artificial intelligence model to predict acute critical illness from electronic health records.

Acute critical illness is often preceded by deterioration of routinely measured clinical parameters, e.g., blood pressure and heart rate.

Study on wideband tympanometry and absorbance within a Danish cohort of normal hearing adults.

Purpose: The objectives of this study was to present wideband tympanometry (WBT) data and absorbance with normal hearing and normal middle ear status.

Methods: Data were collected in 99 adult Caucasians with normal hearing and middle ear status. Energy absorbance was measured with an Interacoustics Titan using clicks for 1/24-octave frequency-intervals (0.

General practitioners' perspectives on chronic care consultations for patients with a history of cancer: a qualitative interview study.

Background: General practitioners (GPs) are responsible for managing chronic care in the growing population of patients with comorbid chronic conditions and cancer. Studies have shown, however, that cancer patients are less likely to receive appropriate chronic care compared to patients without cancer. Patients say that how GPs engage in the care of comorbidities influences their own priority of these conditions.

DeepQSM - using deep learning to solve the dipole inversion for quantitative susceptibility mapping.

Quantitative susceptibility mapping (QSM) is based on magnetic resonance imaging (MRI) phase measurements and has gained broad interest because it yields relevant information on biological tissue properties, predominantly myelin, iron and calcium in vivo. Thereby, QSM can also reveal pathological changes of these key components in widespread diseases such as Parkinson's disease, Multiple Sclerosis, or hepatic iron overload. While the ill-posed field-to-source-inversion problem underlying QSM is conventionally assessed by the means of regularization techniques, we trained a fully convolutional deep neural network - DeepQSM - to directly invert the magnetic dipole kernel convolution.

'More constricting than inspiring' - GPs find chronic care programmes of limited clinical utility. A qualitative study.

Background: As in other countries, Danish health authorities have introduced disease management programmes (DMPs) to improve care quality. These contain clinical practice guidelines (CPGs) and guidelines for patient stratification based on doctors' assessments of disease severity and self-care. However, these programmes are challenged when patients have complex chronic conditions.

Life goes on… Patient perspectives on having a cancer diagnosis and other comorbid diseases: A qualitative study.

Objectives: Due to a growing population with both cancer and chronic diseases, we explored patients' experiences of living with a cancer diagnosis and comorbidities, the possible effects on everyday living and management of comorbidities.

Methods: Semi-structured interviews were conducted during 2016 with 15 patients in Denmark, with finished cancer treatment and preexisting comorbidities. Analysis was performed by Systematic Text Condensation.

'I've put diabetes completely on the shelf till the mental stuff is in place'. How patients with doctor-assessed impaired self-care perceive disease, self-care, and support from general practitioners. A qualitative study.

Objective: This paper investigated patients' experiences of disease and self-care as well as perceptions of the general practitioner's role in supporting patients with impaired self-care ability.

Design: Qualitative interviews with 13 patients with type 2 diabetes, concurrent chronic diseases, and impaired self-care ability assessed by a general practitioner. We analyzed our data using systematic text condensation.

How general practitioners perceive and assess self-care in patients with multiple chronic conditions: a qualitative study.

Background: It is not known how general practitioners (GPs) perceive the concept of self-care and how they assess self-care ability in patients with multiple chronic conditions. As a part of the strategy to improve the care of people living with chronic conditions, disease management programs in Denmark require GPs and other health care workers to assess and support patients' self-care ability. The aim of the present study was to explore GPs' perceptions and assessment of self-care ability in patients with multiple chronic conditions who have difficulty following a given treatment.

Tattooist-customer relationships in a diversified environment of professional tattooists and 'scratchers'.

The world of tattooing and body art has never been like it is today. This chapter seeks to investigate this situation through the lens of tattooing. One of the areas in which tattooing has changed is the relationship between the tattoo artist and his or her clients.

[Increasing shortage of general practitioners in social deprived Danish communities].

The increasing shortage of general practitioners (GPs) in Denmark is expected to continue until 2020. This study investigates the development of GP shortage in the communities of Region of Zealand in relation to patients' social deprivation. From 2010 to 2013 the number of GPs in the most affluent communities decreased by 2.

Kinetics of DNA duplex formation: A-tracts versus AT-tracts.

The hybridisation and melting of DNA strands are critical steps in many biological processes, but still a deeper understanding of the kinetics is lacking. This is evident from the absence of a clear correlation between rate constants for duplex formation and the number of bases in the strand or the sequence. Here we have probed differences between formation times of A-tracts and AT-tracts by studying complementary model strands mainly comprised of adenine (A) and thymine (T) in stopped-flow (SF) experiments.

Negative inotropic and hypotensive effects of the superoxide dismutase mimetic tempol in pigs.

Through interference with free radicals, the nitroxide tempol potentially increases bioavailability of nitric oxide (NO) and along with modulation of potassium channels reduces blood pressure (BP). We studied whether tempol in pigs lowers BP by mechanisms sensitive to inhibition of NO synthase or large conductance calcium-activated potassium channels (BKCa). The cardiovascular effects of intravenous tempol (25-50mg/kg) were examined in anesthetized pigs with myocardial function being evaluated by echocardiography.