[Topical treatment with eberconazole of the experimental guinea pig cutaneous candidosis.].

Eberconazole is a new azole antifungal drug for topical treatment of superficial mycoses. The usefulness of this drug was evaluated in an experimental model of cutaneous candidosis in guinea pigs comparing with the classical clotrimazole in a single blind trial. Twenty-five animals were inoculated in two symmetrical areas of the back with Candida albicans developing skin infection.

[Oral terbinafine for the tinea unguium of the toenails. Efficacy between 12 and 24 weeks of treament.].

Terbinafine 250 mg po daily was administered to 21 patients affected by tinea unguium of the toenails. In 14 cases Trichophyton rubrum was the aetiological agent while Trichophyton mentagrophytes var. interdigitale affected the rest.

Immunochemical characterization of somatic and metabolic antigens of 4 species of Aphanoascus: preliminary results.

Aphanoascus spp. are keratinophylic fungi occasionally described as etiological agents of tinea-like dermatomycoses. The goal of this work was to immunochemically characterize somatic and metabolic soluble antigens prepared from 4 species of Aphanoascus.

Aspergillus versicolor as cause of onychomycosis: report of 12 cases and susceptibility testing to antifungal drugs.

Background: Onychomycoses caused by opportunistic moulds are not well understood, and many are due to Scopulariopsis brevicaulis and other species. Aspergillus versicolor is not documented as an etiological agent in most studies. We have found an increasing prevalence of this species which is involved in 5.

Candiduria in non-neutropenic critically-ill surgical patients. Detection of IgA, IgG and IgM antibodies to Candida albicans by germ tube immunofluorescence.

The significance of indirect immunofluorescence using Candida albicans germ tube as well as blastospore antigens in the diagnosis of isolated candiduria in non-neutropenic, critically-ill surgical patients was assessed. Ten patients with isolated candiduria, 12 with systemic candidosis and 10 with multifocal muco-cutaneous candidosis were included in the study. The sera of another 10 critically-ill patients with no signs of candidosis served as controls.

Aspergillus fumigatus somatic antigens: comparison between two methods of preparation and immunochemical characterization.

Aspergillus fumigatus and other species of the same genus can cause different pathological processes amongst which can be found pulmonary hypersensitivity, intracavitary colonization and invasive and disseminated aspergillosis. The diagnosis of these processes is helped in a great way by the immunological response of the patient to Aspergillus antigens or by the detection of these as a metabolic product in blood and other fluids such as urine. To date, no firm agreement exists regarding the best preparation and standardization technique of aspergillar antigens, which is however the most important step towards the development of immunological diagnostic tests.

[Identification of yeasts of the Candida genus with a growth inhibition system: Microring YT].

Background: It has been observed an spectacular increasing of opportunistic Candida yeast infections. Many of them are fatal, and rapid and effective identification of the infecting species contributes to start the correct treatment. Several new methods for yeast identification have become available; Microring YT is one of these methods based on the growth inhibition by 6 different chemical products.

Extensive dermatophytoses caused by Trichophyton mentagrophytes and Microsporum canis in a patient with AIDS.

Retrospective studies have shown the occurrence of episodes of deep or superficial fungal infections in 58 to 81% of HIV/AIDS patients as a result of impairment of cell immunity. We describe a case of disseminated cutaneous dermatophytoses caused by Trichophyton mentagrophytes and Microsporum canis in a patients with AIDS. Diagnostic and therapeutic problems in relation to this unusual presentation are emphasized as well as the importance of an early mycologic diagnosis to prescribe antifungal therapy.